In the present study, an efficient protocol has been developed for callus induction and production of RA in callus culture of Satureja khuzistanica for the first time. In-vitro callus induction was achieved from young shoot tip explants cultured on MS and B5 media supplemented with different concentrations of IBA (0.1, 1.0, 2.0 and 5.0 mgL(-1)) solely or in combination with cytokinins BAP and K...

background & aim: lemon verbena (lippia citriodora h.b.k.) is a richly scented herb and has a long history as a sacred and medicinal plant. select an appropriate medium in tissue culture is a necessity for success experimental: to evaluate the effect of 10 medium of previous researches for lippia micropropagation (1- ms medium supplemented with bap (3 mgl-1) + iba (0.1 mgl-1) + activated ch...

The Lethal giant larvae (Lgl) gene encodes a cortical cytoskeleton protein, Lgl, and is involved in maintaining cell polarity and epithelial integrity. Previously, we observed that Mgl-1, a mammalian homologue of the Drosophila tumor suppressor protein Lgl, is subjected to degradation via ubiquitin-proteasome pathway, and scaffolding protein RanBPM prevents the turnover of the Mgl-1 protein. Co...

Micropropagation of Kainth using nodal explants was carried out in tissue culture laboratory, Department of Fruit Science, Punjab Agricultural University, Ludhiana during 2011-13. The effect of various media {1/2 MS (M1), MS (M2) and WPM (M3)} and growth regulators (BAP, IBA and NAA) on establishment, proliferation and rooting was studied. Per cent necrotic culture was found to be influenced by...

The endocannabinoids (eCBs) anandamide and 2-arachidonoyl glycerol (2-AG) are inactivated by a two-step mechanism. First, they are carried into cells, and then anandamide is hydrolyzed by fatty acid amide hydrolase (FAAH) and 2-AG by monoacylglycerol lipase (MGL). Here we provide evidence for a previously undescribed MGL activity expressed by microglial cells. We found that the mouse microglial...

An investigation was carried out to decipher the effect of genotypes and concentrations growth regulators for callus induction subsequent plant regeneration from mature seeds rice. Two local rice cultivars viz. Nayanmony Kalomona two 2, 4-D NAA were used evaluate their performance. The cultured under aseptic condition onto MS basal medium at varying combinations (1.0, 1.5 2.0 mgL- 1) (0.0, 0.5 ...

Monoacylglycerol lipase (MGL) is a multifunctional serine hydrolase, which terminates anti-nociceptive endocannabinoid signaling and promotes pro-nociceptive prostaglandin signaling. Accordingly, both acute nociception and its sensitization in chronic pain models are prevented by systemic or focal spinal inhibition of MGL activity. Despite its analgesic potential, the neurobiological substrates...

In atopic dermatitis (AD) and psoriasis (Pso), inflammatory skin diseases with a high patient burden, understanding which subsets of dendritic cells (DCs) macrophages (MØs) are involved in the disease pathogenesis remains key to developing effective treatments. Limited subpopulations DCs MØs that thought drive Th2-mediated immune responses mice express macrophage galactose-type C-type lectin (M...