Introduction: During the last decade, advances in tissue engineering and stem cell-based tooth regeneration have provided realistic and attractive means of replacing lost or damaged teeth. The first adult stem cells isolated from dental tissues were dental pulp stem cells (DPSCs). When transplanted with hydroxyl apatite/tri calcium phosphate (HA/TCP) powder, they formed a dentin-like structure...

Objective(s): In some previous studies, the extract of embryonic carcinoma cells (ECCs) and embryonic stem cells (ESCs) have been used to reprogram somatic cells to more dedifferentiated state. The aim of this study was to investigate the effect of mouse ESCs extract on the expression of some pluripotency markers in human adipose tissue-derived stem cells (ADSCs). Materials and Methods: Human A...

background: transplantation approaches are interventions currently available to apply to the devastating problem of spinal cord injury (sci). olfactory ensheathing cell (oec) and embryonic stem cell (esc) are considered to be promising therapeutic strategies . in this study, we compared the potential use of oecs and neurally pre-differentiated escs in contusion spinal cord. methods: oecs were h...

stem cells are the cells having some distinguishing characteristics like longevity, high capacity of self-renewal and differentiation, quiescence and highly error-free proliferation. almost all stem cells have the potential of lineage reprogramming, i.e. inter-conversion of cell lineages. they also have the potential to differentiate into almost all kinds of cells. these cells have been found i...

stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. they are found in multicellular organisms. in mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. in ad...

Embryonic Hematopoiesis In article number 2205345, Fudi Wang, Junxia Min, and co-workers identify demonstrate indispensable function of zinc transporter SLC39A10 (ZIP10) its mediated homeostasis for maintaining the survival fetal hematopoietic stem/progenitor cells. As most important importer on cell membrane stem cells, ZIP10 functions as a gatekeeper (like vacuum to transport across membrane)...

stem cell research has received considerable attention since the discovery that adult stem cells havethe capacity to form many different tissue types. stem cells are a booming field for the researchand have been extensively studied in the field of medicine, as well as dentistry. their applicationin oncology has been a boon to many of the patients. dental stem cells have been novel approachto tr...

Background Specific growth factors and feeder layers seem to have important roles in in vitro embryonic stem cells (ESCs) differentiation. In this study,the effects of bone morphogenetic protein 4 (BMP4) and mouse embryonic fibroblasts (MEFs) co-culture system on germ cell differentiation from mouse ESCs were studied. MaterialsAndMethods Cell suspension was prepared from one-day-old embryoid bo...