Planning for treatment of gastric adenocarcinoma in a patient previously treated with partial gastrectomy for primary gastric lymphoma is difficult. Long term survival of advanced gastric adenocarcinoma is poor with therapy and even worse without treatment. The only potentially curative treatment for gastric adenocarcinoma is surgical resection with adequate margins. Palliative surgery ameliora...

This study aims to detect the mRNA of p53β and Δ133p53 isoforms in three gastric carcinoma cell lines and tissues of superficial gastritis, atrophic gastritis, gastric carcinoma, or paracancerous area. Nested reverse transcription PCR was used to detect the mRNA of p53β and Δ133p53 isoforms in tissues of superficial gastritis, chronic atrophic gastritis, gastric cancer cell lines (SGC-7901, MKN...

Gastric cancer is the fourth most common cause of malignancy death in the world, which also has a high prevalence in Iran. Caspase 3 gene is considered one of the major genes related to gastric cancer. The present study aimed to investigate the relationship between rs12108497 polymorphism of Caspase 3 gene. Due to the fundamental role of caspases, we have considered an SNP of Caspase 3 (common ...

conclusions abnormal e-cadherin expression is a common phenomenon in gastric adenocarcinoma. the study showed a significant correlation between abnormal e-cadherin expression and tumor grade and regional lymph node involvement; so, abnormal e-cadherin expression may be used as a predictive factor for tumor invasiveness in gastric adenocarcinoma. materials and methods a historical cohort survey ...

Rates of esophageal adenocarcinoma and gastric cardia adenocarcinoma have increased, while rates of esophageal squamous cell carcinoma (ESCC) and gastric noncardia adenocarcinoma have decreased, suggesting distinct etiologies. The authors prospectively investigated the associations of alcohol and tobacco with these cancers in 474,606 US participants using Cox models adjusted for potential confo...

BACKGROUND Ectopic gastric mucosa (EGM) otherwise termed gastric heterotopia or gastric inlet patch occurs in approximately 2.5% of the population. Adenocarcinoma uncommonly involves the upper oesophagus, rarely arising from gastric heterotopia or submucosal glands. Currently, there are 58 cases in the literature of oesophageal adenocarcinoma arising within areas of EGM. To date no paper has di...

background little is known about the possible influence of demographic and histological risk factors on the survival of patients with esophageal and gastric cancer. objectives based on the available registry and follow-up information, this study compares 1-5 year survival rate of gastric and esophageal cancer. patients and methods through a concurrent (prospective) cohort study, all 366 patient...