Licorice (Glycyrrhiza glabra L.) as a strategic and highly valuable medicinal plant in Iran with numerous beneficial pharmaceutical properties contributes substantially to Iranian herbs exports. In the present study, a variation on the phytochemical and antioxidant activity of 25 populations of valuable and profitable medicinal plant of G. glabra was investigated. The climate variables and soil...

The phytochemical composition of plants is very diverse and includes many biologically active substances, their combination determines the pharmacological activity. This article examines underground part Paeonia tenuifolia L. leaves Petrocoma hoefftiana (Fisch.) Rupr. It was found that studied objects contain glycyrrhizic acid, peucedanin, flavonoids, phloroglucides, tannins, ascorbic acid. can...

The current study examined the effectiveness of glycyrrhizic acid (GA) in reducing cell viability and inducing apoptosis in human chronic myeloid leukemia (CML) in vitro and a mouse lymphoma in vivo. Additionally, we assessed GA as a candidate for combinational therapy in CML along with the current frontline treatment, imatinib (IM). Treatment of K562 CML cells with GA alone resulted in signifi...

The aim of this study was to investigate the correlation between root respiration and the percentage of active components in licorice (Glycyrrhiza uralensis Fisch.), in order to provide a foundation for the regulation and modulation of the quality of G. uralensis. Respiration efflux of annual and biennial G. uralensis was determined using a Li-7000 CO2/H2O analyzer. The root systems were scanne...

The study synthesized a supramolecular complex of glycyrrhizic acid and β -indolyl-3-acetic in 4:1 ratio isolated from the root plant licorice (Glycyrrhiza glabra L.). resulting GA:IAA (4:1) was chemically identified based on comparison IR – Fure spectra starting agents.

In our current study, a newer amine functionalized guar gum derivative was studied for its efficacy in colonic drug delivery. Glycyrrhizic acid mono-ammonium salt was used as the model drug. Drug-loaded microparticles were formulated by ionic crosslinking using sodium tripolyphosphate. The Scanning Electron Microscopic study revealed spherical particles of sizes from 4.9 ± 3.8 μm to 6.9 ± 3.9 μ...

© 2012 Dushkin et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Complexes of Polysaccharides and Glycyrrhizic Acid with Drug Molecules − Mechanochem...