نتایج جستجو برای: ischemic reperfusion
تعداد نتایج: 113044 فیلتر نتایج به سال:
Abstract: Background: Neuroprotection is one of considerable interest in search novel therapies to improve ischemic brain damage the present scenario. The objective investigation study actions Talinum triangulare cerebral ischemia/reperfusion induced oxidative stress Wistar rats and in-vitro antioxidant actions. Methods: Four different groups adult are selected for where group III IV treated 15...
objective(s) the aim of this study was to investigate the overall effect of cardiac vasoactive factors during coronary occlusion and reperfusion on peripheral vascular tone, using a sequential isolated rabbit heart-ear perfusion model. materials and methods isolated ears were perfused with the effluent of isolated hearts subjected to ischemia (30 min) and reperfusion (180 min, n=6). the compara...
Objective(s): The aim of this study is to determine the therapeutic effects of pomegranate seed oil, which is a powerful antioxidant and anti-inflammatory agent, on ovarian-ischemia and reperfusion injury in rats.Materials and Methods: Fifty-six female albino Wistar rats were divided into 7 equal groups. Group 1; Sham Operation, Group 2; Ischemia, Group 3; Ischemia + Reperfusion, Group 4; Isch...
Introduction: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage. Evidence indicates that exercise reduces the ischemia and reperfusion-induced brain damages in animal models of stroke. In the present study, the effect of exercise preconditioning on brain edema and neurological movement disorders followin...
Introduction: Ischemia plays an important role in the development of pathologic in various neuropathies, and reperfusion improves the pathological and physiological abnormalities of ischemic nerves. In this study, the effect of shortreperfusion time after short time ischemic on spinal cord of rat was investigated. Methods: Eighteen rats (Sprague-Dawley, 250-350 g), were divided into 3 groups: g...
Background& objectives: Renal ischemia-reperfusion (IR) damage occurs during renal transplantation in end-stage renal disease (ESRD) patients which activate immune responses. Inflammatory responses by increased levels of cytokines can lead to acute kidney injury (AKI) that contributes to the loss of renal grafts and graft dysfunction. The purpose of this study was to review the therapeutic effe...
Introduction: Binding of mature brain derived neurotrophic factor (BDNF) to tyrosine kinase B (TrkB) receptor leads to cell survival, while proBDNF binding to p75 receptor leads to cell death. Thus the aim of the present study was to investigate the effects of eight weeks pre-conditioning endurance training on BDNF, TrkB, proBDNF and p75 levels in the hippocampus male rats following ischemic re...
Background: It has been reported that the chronic oral administration of garlic homogenate protected the rat heart from in vitro ischemic reperfusion injury. However, the biological effects of garlic juice on the heart are expected to be different from oral administration of it. Objective: the present study was designed to investigate the effect of garlic juice on the isolated rat heart in is...
Background and purpose: Sesame oil (SO) is known to have antioxidant and anti-inflammatory properties and may produce protective effects against ischemic stroke-induced brain injuries. We examined the effects of treatment with SO on cerebral infarction and edema in a rat model of ischemic stroke. Materials and methods: Thirty male Sprague Dawley rats were divided into sham, ischemic, and isch...
Resume. The search for new drugs with cytoprotective and anti-ischemic activity is an urgent task of modern pharmacology. These properties are necessary the complex protection renal parenchyma during organ preservation operations (renal resection), most often carried out in conditions thermal ischemia. Only combined use highly effective skill operating surgeon can prevent development acute inju...
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