objective(s):p in vitro chemosensitivity and resistance assays (csras) are a promising tool for personalized treatment of glioblastoma multiform (gbm). these assays require a minimum of 1 to 2 g of tumor specimen for testing, but this amount is not always accessible. we aimed to assess the feasibility and validity of utilizing stereotactic biopsies of gbm in csras. materials and methods: single...

gene-testing program, but various initiatives are getting under way. Several insurance plans have implemented rules for covering certain genetic tests, such as the BRACAnalysis (Myriad Genetics) for breast cancer testing. Some plans have eligibility requirements or prior authorization protocols for the BRACA gene test, one that has the widest set of gene-testing programs in the industry. Anothe...

The following true story, although pertaining to a rare condition, is typical of medicine practised in hospitals and doctors' surgeries every day all over the world. Mrs M's district nurse phones me-she is with Mr and Mrs M at their house dressing a leaking exophytic chest wall lesion. She can see a 'liver like substance' extruding from a small inferior wound, there is some fresh blood, and she...

[No Abstract Available].

The idea that one drug treatment can fit all has been waning for decades, but up until a decade ago, we lacked the technology and infrastructure to implement novel medical approaches that would give rise to personalized medicine. Still in its embryonic stages, personalized medicine, also known as precision medicine, aims to synthesize relevant genetic and genomic information from a patient to h...