BACKGROUND Administration of parenteral doses with microbial contamination can lead to infective morbidity or death. AIM To test whether aseptic preparation of parenteral doses or additives to sterile doses undertaken in dedicated pharmaceutical rather than clinical environments reduces the risk of microbial dose contamination. METHODS Data identified from a systematic review were examined ...

On-line preparation, i.e., continuous mixing and immediate use, was introduced for dialysis fluid in 1964, and it contributed significantly to the expansion of dialysis therapy through simplified handling, improved microbiology, and enhanced efficiency. On-line prepared replacement solution for hemofiltration was shown to be clinically safe as early as 1978, but the implementation was delayed f...

Background: Surgical site infection (SSI) remains a concern in shoulder surgery, especially during arthroplasty. Whilemany studies have explored the characteristics and efficacy of different sterilizing solutions, no study has evaluated themethod of application. The purpose of this study was to compare two popular pre-surgical preparatory applications (two4 x 4 cm gauze sponges and applicator s...

Case Description- Three domestic short haired cats (2, 5 and 4 years of age) were presented to the Madras Veterinary College Teaching Hospital, with the history of large chronic, full thickness wounds on the right lateral cervical, left caudal forearm and right lateral thoracic region respectively. Etiology of the wounds was trauma in two cases and thermal burns in the third ca...

UNLABELLED Our objective was to compare the stability of Kinevac when reconstituted with sodium chloride injection, USP, 0.9%, versus the manufacturer's recommended sterile water for injection, USP, and to determine the effects on stability of deviating from the manufacturer's recommended methods of product preparation. METHODS Kinevac was reconstituted with either sterile water or 0.9% sodiu...

Shoulder arthroscopy offers a minimally invasive surgical approach to treat a variety of shoulder pathologies. The patient can be positioned in either the lateral decubitus or the beach chair position. This note and accompanying video describe the operating room setup for shoulder arthroscopy in the lateral decubitus position, including positioning of the arms, head, and sterile preparation and...