BACKGROUND Several strategies to reduce construct stiffness have been proposed to promote secondary bone healing following fracture fixation with locked bridge plating constructs. However, stiffness reduction is typically gained at the cost of construct strength. In the present study, we tested whether a novel strategy for stiffness reduction, termed far cortical locking, can significantly redu...

This paper presents a novel RF MEMS (Micro Electromechanical System) fixed-fixed switch for very fast switching. Using the obtained equations, the switching time depends on the stiffness and effective mass of the switch beam so that the switching time will be decreased by higher stiffness (spring constant) and lower effective mass. In new design, the suspension bridge is a three-layer beam so t...

INTRODUCTION: The stiffness of a fixation construct affects the mechanism and progression by which a fracture heals. Locked plating constructs have improved fixation strength in weak bone, but their relatively high stiffness may suppress interfragmentary motion (IFM) to a level insufficient for optimal promotion of secondary bone healing.[1] This is especially of concern when locked plates are ...

The effects of the nitric oxide (NO) donor spermine NONOate (Sp-NO, 1.0 mM) on cross-bridge recruitment and cross-bridge cycling kinetics were studied in permeabilized rabbit psoas muscle fibers. Fibers were activated at various Ca2+ concentrations (pCa, negative logarithm of Ca2+ concentration), and the pCa at which force was maximal (pCa 4.0) and approximately 50% of maximal (pCa50 5.6) were ...

Methods: A total of 25 fresh-frozen cadaveric shoulders were randomized into 5 suture configuration groups: single-row repair with simple stitch technique; single-row repair with modified Mason-Allen technique; double-row Mason-Allen technique; doublerow cross-bridge technique; and double-row suture bridge technique. Load and displacement were recorded at 100 Hz until failure. Stiffness and bon...

The kinetics of Ca(2+)-induced contractions of chemically skinned guinea pig trabeculae was studied using laser photolysis of NP-EGTA. The amount of free Ca(2+) released was altered by varying the output from a frequency-doubled ruby laser focused on the trabeculae, while maintaining constant total [NP-EGTA] and [Ca(2+)]. The time courses of the rise in stiffness and tension were biexponential ...