BACKGROUND Iron Deficiency Anemia (IDA) is an important health problem all around the world especially in developing countries. In the Mediterranean countries another prevelant reason of anemia is Thalassemia. Certain strategies had been established as a government policy to reduce prevalence in North Cyprus, such as pre-marital screening of Thalassemia. The prevalence of thalassemia trait has ...

ABSTRAKPrevalensi penyakit thalasemia di Indonesia, seperti Kabupaten Ciamis mengalami peningkatan dalam kurun waktu lima tahun terakhir. Prinsip utama pencegahan munculnya penderita baru adalah dengan mencegah kelahiran bayi thalasemia. Program yang efektif untuk menanggulangi masalah tersebut pendidikan publik Kegiatan program dapat menjadi solusi bagi permasalahan kegiatan edukasi thalassemi...

Thalassemia is a hereditary blood disorder that results from genetic defects causing deficient synthesis of hemoglobin polypeptide chains. Although thalassemia mostly affects developing countries, there is limited knowledge of its accurate frequency and distribution in these regions. Knowing the prevalence of thalassemia and the frequency of responsible mutations is therefore an important step ...

We report a retrospective analysis carried out on 23,485 subjects submitted to a screening program from 2000 to 2006. Of these subjects, 3,934 had borderline HbA(2) values from 3.1 to 3.9%; 410 samples, analyzed previously using PCR methods and sequencing because all of these were partners of a carrier of classical beta-thalassemia, were selected for statistical analysis. Of 410 subjects, 94 (2...

BACKGROUND Hepatitis C virus (HCV) is the leading cause of transfusion transmitted infections (TTIs) among patients with β-thalassemia major. A high prevalence of HCV was reported among these patients. The aim of this study is seeking the trend of the prevalence of HCV infection among the patients with b-thalassemia major in Guilan province, Northern Iran over a 10-year period. METHODS A retr...

This Paper is to describe the economic burden of thalassemia as a major health problem in thalassemia belt countries like Iran. Great emphasis is placed on prenatal diagnosis to prevent the disease, as the “economic” solution from a health care policy viewpoint. The alternative method of the current screening program in Iran is outlined and discussed especially with respect to the “cost-effecti...

Thalassemia adalah kelainan gen yang ditandai dengan anemia parah. Penderita membutuhkan transfusi darah berkala untuk dapat bertahan hidup. Kelainan ini ditemukan di seluruh dunia termasuk Indonesia. Prevalensi pembawa thalassemia Indonesia mencapai 3,8%. Pembawa tidak menunjukkan gejala, sehingga dimungkinkan pernikahan antara berisiko melahirkan anak sebesar 25%. dikendalikan dan dicegah pro...

Coinheritance of α-thalassemia and hemoglobin E (Hb E) is prevalent in Thailand, where the gene frequencies of thalassemia and hemoglobinopathies are high. Hb E carriers with, concomitant inheritance of α-thalassemia 1 are known to have a lower level of Hb E. In this study, we reviewed the Hb E levels in Hb E carriers, who either had or did not have Southeast Asian (SEA)-type α-thalassemia, in ...