a nested polymerase chain reaction (pcr) assay with two pairs of primers was applied for the detection of m. tuberculosis complex dna in specimens of 51 patients. of these, 31 clinically diagnosed patients (group i) recruited from july 1996 to june 1997 were given antituherculous chemotherapy from one to six months with standard daily regimen (isaniazid, 5 mg/kg; rifampin, 10 mg/kg; pyrazinamit...

introduction: limited data are available on the relationship between nutritional status and tuberculosis. the aim of this study was to evaluate and compare the body mass index (bmi) and serum albumin level in patients with active tuberculosis (atb) and latent tuberculosis (ltb). materials and methods: a cross-sectional study was conducted on 17 patients newly diagnosed with pulmonary tb  who we...

background: tuberculosis (tb) is a major worldwide public health problem. the incidence of tuberculosis has decreased in iran in recent years. however, despite this dramatic decline, tuberculosis is still considered to be a major health problem in iran. objectives: the aim of this study was to investigate the epidemiological situation and main characteristics of tuberculosis in iran. patients a...

conclusions concurrent pulmonary nocardiosis and tuberculosis is frequent in hiv-infected patients. rapid and sensitive methods such as pcr are recommended for detection of such co-infections. results from 157 sputum specimens, positive samples by acid fast staining, culture and pcr for m. tuberculosis were reported for 7.6% (12/157), 10.1% (16/157) and 7% (11/157) of samples, respectively. no ...

Background & Aims: Tuberculosis is one of the most important causes of mortality in the world and if it is not treated, 50 – 65% of patients would die in five years. Chest X-ray has an important role in the diagnosis of TB and early diagnosis and treatment prevent tuberculosis transmission. In this study we evaluated radiologic manifestations of patients with smear positive pulmonary tubercu...

drug resistance (especially multiple drug resistance) in mycobacterium tuberculosis makes global concerns in treatment and control of tuberculosis. rapid diagnosis of drug resistant strains of the bacteria has vital importance in the prognosis of the disease. the aim of this study was to identify the mutations responsible for drug resistance in mycobacterium tuberculosis strains derived from pa...

persons infected with the human immunodeficiency virus (hiv) are particularly susceptible to tuberculosis, either by latent infection reactivation or by a primary infection with rapid progression to active disease. this study was done to determine the frequency of tuberculosis infection among iranian patients with hiv/aids. a total of 262 hiv/aids patients attending all three hiv/aids health ca...