from 1365 to 1382, 205 cases of acute lymphoblastic leukemia (all) were refered to our center. 160 cases achived complete remission and entered our clinical trial of cns relapse which were under consideration. the patients included 98 men and 62 women with an average age of 32 years (range 4-61 years). 160 of 205 cases had complete remission with a rate about 78%.the latter group was entered in...

Abstract BACKGROUND Breast cancer is the most common in world and second to metastasize central nervous system (CNS). CNS-metastases are type of brain tumor have a rising incidence. They associated with neurologic morbidity mortality remain major clinical challenge. Survival withCNS-metastases short median survival order months. The incidence 5.1% breast however true prevalence not known; at au...

Background: The aim of this study was to review and characterize the pattern of CNS lesions in patients suffering from AIDS and to correlate these patterns with clinical disorders. Method: The MR scan, medical records and laboratory findings of 58 AIDS patients were reviewed retrospectively during April 1994 to November 1997 at the Olive view/UCLA and Shiraz Medical Centers, and the patterns o...

the occurrence of neonatal seizures may be the first and perhaps, the only clinical sign of a central nervous system (cns) disorder in the newborn infant. identifying the etiology for the neonatal seizures is/critical to prognosis and treatment. the most common etiology for neonatal seizures is hypoxic-ischemic encephalopathy. seizures may indicate the presence of a potentially treatable etiolo...

central nervous system ranks among the favorite sites to get involved by nocardia astroides. this opportunistic organism complicates many disorders characterized by cellular or humoral immunity disturbances.a 36-year-old woman is being presented, known to have systemic lupus erythematosus (sle) and having received a two year course of corticosteroid treatment. cerebellar abscess was found on di...

Bone morphogenetic protein 9 (BMP9), also known as growth differentiation factor 2 (GDF2), is a member of the transforming ? (TGF ?) superfamily. Although BMP9 plays pivotal roles during development, including angiogenesis, hematopoiesis, hepatogenesis, osteogenesis, and glucose metabolism, little information available for expression in central nervous system (CNS). We, thus, investigated adult...