background acute upper gastrointestinal bleeding (ugib) is a common medical emergency and is known as one of the main causes of mortality and morbidity. this research was conducted to study the causes and risk factors for ugib, in a referral center. methods in this cross sectional study, carried out in a one year period, all patients with acute ugib living in khorramabad city and surrounding ar...

acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we rep...

the  non-classical mhc  class-i mainly involves in the  regulation of  innate  immune responses where hla-e  plays a significant role in the cell identification by natural killer cells. hla-e is a main regulatory ligand for natural killer cells and given the importance of these effector cells in hematopoietic stem cell transplantation, we investigated the effect of hla-e polymorphisms on post-h...

conclusions crp, a well-known acute phase reactant that increases rapidly in various inflammatory processes, can be accepted as a strong predictor in classifying different grades of the disease, and treatment can be reliably planned according to this classification. results mean crp levels of groups were found to be significantly different, 18.96 mg/l in group i, 133.51 mg/l in group ii, and 23...

Kawasaki disease is an acute inflammatory disorder of medium-sized arteries that predominantly affects cardiac coronary arteries and children under the age of 5 years. Cardiac involvement usually happens later than 10 days after the onset of illness. Most of cardiac complications are coronary artery abnormalities (ectasia or aneurysms) and subclinical myocarditis. Clinical myocarditis (symptoma...

introduction acute disseminated encephalomyelitis (adem) is an acute inflammatory and demyelinating disease of the central nervous system, resulting in various neurological symptoms. usually, the disease appears following vaccination or systemic viral infections. in rare cases, the disease appears following pneumococcal infections. case presentation the patient was a 27 year-old man who was ref...

b ackground: toxoplasmosis is a serious disease in immunocompromised patients and pregnant women. differentiation of acute and chronic infection is a major challenge in serodiagnosis of the disease. since the aim of this study was to assess the diagnostic utility of recombinant sag1 (rec- sag1) for the detection of toxoplasma -specific igm antibodies in human sera, by an enzyme-linked immunosor...

Background: Patients who undergo major orthopedic surgery are at risk of acute kidney injury (AKI) due to blood loss, electrolyte disorders, infection, and the presence of other co-morbidities. In this study, the frequency and risk factors of AKI were investigated. Objective & Methods: This study is a cross-sectional-analytical study with a sample size of 180 people. The studied population wer...