The population pharmacokinetics on tazobactam/piperacillin (TAZ/PIPC; 1:8, 4.5 g x 3) was analyzed in Japanese patients with community-acquired pneumonia using the Nonlinear Mixed Effect Model version VI. Analysis by the one-compartment model yielded the following results for PIPC: total clearance (CL) = 8.22+(Ccr-71.4) x 0.0561 (L/hr), distribution volume (Vd) = 13.7 (L). The pharmacokinetic p...

We examined the potential involvement of two CC chemokine receptors (CCRs), CCR-1 and CCR-3, in the functional activation of granulocyte-macrophage colony-stimulating factor (GM-CSF) plus interleukin-4 (IL-4)-generated human peripheral blood monocyte-derived immature dendritic cells (DCs). Flow cytometric analysis showed that CCR-1, CCR-3, CCR-5, and CXC chemokine receptor (CXCR)-4 were express...

This study investigates the mode identifiability of a multi-span cable-stayed bridge in terms of a benchmark study utilizing stabilization diagrams of system model identified by means of the stochastic subspace identification (SSI). The cumulative contribution ratios (CCR) estimated from singular values of system model was also considered. Observations demonstrated that wind speed might influen...

Abstract Real-world classification domains, such as medicine, health and safety, finance, often exhibit imbalanced class priors have asynchronous misclassification costs. In cases, the model must achieve a high recall without significantly impacting precision. Resampling training data is standard approach to improving performance on binary data. However, state-of-the-art methods ignore local jo...

In this article, we will estimate efficiency amountof decision-making unit by offering the continuous piecewise polynomialextrapolation and interpolation by CCR model input-oriented on the assumptionthat it is constant returns to scale in different times. And finally, we willestimate efficiency amount of decision-making unit indifferent times byoffering an example.

BACKGROUND AND PURPOSE Comprehensive cardiac rehabilitation (CCR), which integrates structured lifestyle interventions and medications, reduces morbidity and mortality among cardiac patients. CCR has not typically been used with cerebrovascular populations, despite important commonalities with heart patients. We tested feasibility and effectiveness of 6-month outpatient CCR for secondary preven...

Abstract The emission of blast furnace (BF) exhaust gas has been criticized by society. It is momentous to quickly predict the comprehensive coke ratio (CCR) BF, because CCR one important indicators for evaluating emissions, energy consumption, and production stability, also affects composite economic benefits. In this article, 13 data-driven prediction techniques, including six conventional se...

in this article, we will estimate efficiency amountof decision-making unit by offering the continuous piecewise polynomialextrapolation and interpolation by ccr model input-oriented on the assumptionthat it is constant returns to scale in different times. and finally, we willestimate efficiency amount of decision-making unit indifferent times byoffering an example.