Repeated evidence has demonstrated that combined primer-booster immunization regimens can improve both secreted and humoral immune responses to antigens derived from viral, bacterial, and parasitic pathogens. For the present work, we evaluated the synergic serum immunoglobulin G (IgG) and fecal IgA antibody responses elicited in BALB/c mice who were intramuscularly primed with a DNA vaccine, pR...

Irbesartan, a widely prescribed anti hypertensive drug belongs to class II under BCS classification and exhibit low and variable oral bioavailability due to its poor aqueous solubility. It needs enhancement in the dissolution rate in its formulation development. Complexation with β-cyclodextrin (βCD) and use of Crospovidone and PVP K 30 are tried for enhancing the dissolution rate of irbesartan...

Background: Caused by bacterial, viral, and parasitic pathogens, diarrhea is the second leading cause of death among children under five. Two strains of E. coli, namely Enterotoxigenic, ETEC and Enterohemorrhagic EHEC are the most important causes of this disease in developing countries. EHEC is a major causative agent of bloody diarrhea and hemorrhag...

Enterotoxin-producing Escherichia coli (ETEC) are one of the main causative agents of diarrhea in children especially in developing countries and travel diarrhoea in adults. Pathogenic properties of ETEC associated with their ability to produce a heat-stable (ST) and/or heat-labile (LT) enterotoxins, as well as adhesins providing bacterial adhesion to intestinal epithelial cells. This study pre...

millions of diarrheal disease is made by enterotoxigenic e. coli (etec) each year, specifically in developing countries. in the pathogenesis of etec infections, the first phase is sticking of the bacterium to the minute intestinal epithelium, as a result of colonization factors (cfs) mediation and subsequently generate enterotoxins. these cfs in accordance with their structure are diverged into...

In this letter, we discuss the extension of Feynman’s derivation of the equation of motion to the case of spinning particles. We show that a spinning particle interacts only with the electromagnetic and gravitational fields. In the absence of the electromagnetic interactions, we rederive Papapetrou’s equations for spinning particles in the background of the conformal gravity. We also find that ...