background: the trace element copper has been identified as a highly toxic element for sperm. it is known to affect sperm motility in humans and experimental implantation of copper in the epididymis vas deferens and scrotum of mammals has been demonstrated to affect fertility detrimentally. objective: sperm concentration motility vitality and morphology are parameters used to evaluate potential...

We examined the non-opioid actions of various forms of dynorphin A (DynA) on N-methyl-D-aspartate (NMDA) receptor channels in isolated rat trigeminal neurons using the whole-cell patch recording technique. All the dynorphins tested blocked NMDA-activated currents. The blocking actions were voltage-independent. The IC50 was 0.26 microM for DynA(1-32), 6.6 microM for DynA(1-17) 7.4 microM for Dyn...

mycophenolic acid is a secondary extracellular metabolite of penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. the aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by penicillium brevi-compactum atcc16024 was investigated. batch submerged fer...

Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...

background: several compounds obtained from plants have potential insecticidal, growth deterrent or repellent characteristics. the control of hard ticks by non-chemical substances was targeted in this study. methods: the effect of 36 materials on in-vitro ticks was studied, including 2 absolute controls (water only or ab­solute ethyl alcohol only), 6 conventionally used spinosad preparations (a...

rice (oryza sativa l.) is one of the iran's most strategic crops with water shortage as the most important abiotic stress limiting its yield. in the present research the effects of: variety, water regime, nitrogen (n) and phosphorus (p) levels on n, p and k uptake were studied under greenhouse conditions. the experiment design was a factorial one based upon a randomized complete blocks of ...