omalizumab is a recombinant humanized anti-ig e monoclonal antibody used as the third line treatment of chronic spontaneous urticaria (csu). we report four patients with severe antihistamine-resistant csu, who developed angioedema, anaphylaxis and/or flare up of urticaria at different times following omalizumab therapy.

Let $$z_0$$ and $$w_0$$ be given points in the open unit disk $$\mathbb {D}$$ with $$|w_0| < |z_0|$$ , $$\mathcal {H}_0$$ class of all analytic self-maps f normalized by $$f(0)=0$$ . In this paper, we establish third-order Dieudonné’s Lemma apply it to explicitly determine variability region $$\{f'''(z_0): f\in \mathcal {H}_0,f(z_0) =w_0, f'(z_0)=w_1\}$$ for $$z_0,w_0,w_1$$ give form extremal f...

We outline in this paper a suite of methods, and illustrate their use, to empirically determine food self-sufficiency at a relatively small (Local Health Areas) level of geography. Further we have, after identifying regions of lowest food self-sufficiency in British Columbia (BC) superimposed these on regions whose populations have relatively poor dietary ill health. Approximately one third of ...