Although early depletion of noradrenaline is known to affect the morphological development of various structures in the brain, it is not clear what implications this has for adult behaviour. In the present study, 6-hydroxydopamine (6OHDA) was injected into the lateral ventricles of 12 day old rats, permanently destroying most of the noradrenergic innervation of the spinal cord and of all the br...

Although commonly viewed as a sensory information relay center, the thalamus has been increasingly recognized as an essential node in various higher-order cognitive circuits, and the underlying thalamocortical interaction mechanism has attracted increasing scientific interest. However, the development of thalamocortical connections and how such development relates to cognitive processes during ...

Recent outbreaks of Trypanosoma brucei rhodesiense sleeping sickness in Soroti District of eastern Uganda have demonstrated the important role cattle can play as reservoirs of this parasite. To clarify the epidemiological importance of the cattle reservoir, experiments were conducted to determine the ease with which T. brucei is transmitted during the course of its development in Friesian cattl...

Medical product development (MPD) process is highly multidisciplinary in nature, which increases the complexity and the associated risks. Managing the risks during MPD process is very crucial. The objective of this research is to explore risks during MPD in a dental product manufacturing company and propose a model for risk mitigation during MPD process to minimize failure events. A case study ...

Introduction: - Significant increase in usage of silver nanoparticles (AgNPs) in consumer products, has increased its exposures to human and animals. Although there are some reports regarding the effects of AgNPs on complex organisms, no report was found as to its effects on neurobehavioral ontogeny. Methods: To investigate the effects of maternal exposure to AgNPs on development of neu...