background: although the imbalance of cytokines in head and neck squamous cell carcinoma (hnscc) is well known, there is scarce data regarding its occurrence during dysplasia, before the malignant transformation. objective: to determine whether laryngeal dysplasia patients show a different cytokine profile than patients with cancer and healthy controls. methods: seventeen newly diagnosed, untre...

Osmotic stresses, protein insertion or lipid oxidation lead to area increase of self-assembled lipid membranes. However, methods to measure membrane expansion are scarce. Challenged by recent progress on the control of phospholipid hydroperoxidation, we introduce a method to quantitatively evaluate membrane area increase based on the bio-adhesion of Giant Unilamellar Vesicles.

We study the traffic of two types of molecular motors using the two-species asymmetric simple exclusion process (ASEP) with periodic boundary conditions and with attachment and detachment of particles. We determine characteristic properties such as motor densities and currents by simulations and analytical calculations. For motors with different unbinding probabilities, mean-field theory gives ...

Exception handling in Ada has a number of well-known problems. It allows for the propagation of unhandled and anonymous exceptions, it is error-prone and it is inappropriate for some language features including tasking and tagged types. Ada programs with exceptions are difficult to understand, develop, modify or analyse, and the exception handling features can be misused in a number of ways. In...

We examine the dual graph representation of simplicial manifolds in causal dynamical triangulations (CDT) as a means to build observables and propose new based on finite element methods (FEM). In particular, with application FEM techniques, we extract (low-lying) spectrum Laplace-Beltrami (LB) operator Sobolev space ${H}^{1}$ scalar functions piecewise flat compare them corresponding results ob...