The use of placebos is the "gold standard" in studies of investigational drugs, and of other medical procedures as well. Several recent trends have suggested the use of placebos in studies of psychotherapy to isolate effective treatment components, and as a basis for establishing lists of empirically supported treatments. Unlike within the domain of medicine, in which the logic of placebos is r...

George F. Vande Woude, Gary J. Kelloff, Raymond W. Ruddon, Han-Mo Koo, Caroline C. Sigman, J. Carl Barrett, Robert W. Day, Adam P. Dicker, Robert S. Kerbel, David R. Parkinson, and William J. Slichenmyer Van Andel Research Institute, Grand Rapids, Michigan; Division of Cancer Treatment and Diagnosis and Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; Johnson & Johnson...

George F. Vande Woude, Gary J. Kelloff, Raymond W. Ruddon, Han-Mo Koo, Caroline C. Sigman, J. Carl Barrett, Robert W. Day, Adam P. Dicker, Robert S. Kerbel, David R. Parkinson, and William J. Slichenmyer Van Andel Research Institute, Grand Rapids, Michigan; Division of Cancer Treatment and Diagnosis and Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; Johnson & Johnson...

prostate cancer is a devastating disease for which current therapies are inadequate. various lines of evidences have suggested the 5-lipoxygenase (5-lox) pathway and the leukotriene receptor pathway are potential targets for prevention or treatment of prostate cancer. thus, search for new anti-cancer drugs targeting 5-lox and leukotriene is very essential and important. the objective of the pre...

Prostate cancer is a devastating disease for which current therapies are inadequate. Various lines of evidences have suggested the 5-lipoxygenase (5-LOX) pathway and the leukotriene receptor pathway are potential targets for prevention or treatment of Prostate cancer. Thus, search for new anti-cancer drugs targeting 5-LOX and leukotriene is very essential and important. The objective of the pre...

Background Although medical oncologists can have an important role in controlling the cost of cancer treatment, there is little information about their attitudes toward the cost of cancer treatment and the impact of cost on their treatment recommendations, especially in low- and middle-income countries (LMICs). In this study, we assessed the attitude of Iranian medical oncologists toward some e...

Optimizing drug combination treatment has been an area of interest for a while, from the beginning with emergence POMP regime. The ability to improve combinations cancer comes up against possibility several limitations, such as lack specificity drugs, generating systemic toxic effects, and also great tumor cells resistant drugs. development nanooncology offers advances in new alternatives cance...