The risk of hypoglycemia is a major barrier to intensifying medical therapy in patients with diabetes who use insulin secretagogues or exogenous insulin.1–3 By promoting the transport of blood glucose into insulin-sensitive tissues, these medications can cause hypoglycemia if their action is not counterbalanced by carbohydrate intake. Conversely, excessive carbohydrate intake can override the e...

AIMS/INTRODUCTION The present cohort study assessed the risk among Japanese men for developing type 2 diabetes, based on the percentage of energy intake from carbohydrates and degree of obesity. PARTICIPANTS AND METHODS The participants were 2,006 male factory employees, and the macronutrient intake of each patient was measured using a self-administered diet history questionnaire. The inciden...

AIMS/INTRODUCTION The pathophysiology of diabetes differs between Asian and Western patients in many ways, and diet is a primary contributor. The present study examined the effect of diet on the efficacy of 25% insulin lispro/75% insulin lispro protamine suspension (LM25) and 50% insulin lispro/50% insulin lispro protamine suspension (LM50) as starter insulin in Chinese and Japanese patients wi...

BACKGROUND The need for long preoperative fasting has been questioned. Recent data shows that intake of an oral carbohydrate-containing clear fluid prior to anaesthesia is safe and may have a positive impact on recovery and metabolic status and could improve glucose tolerance. Such solutions are routinely used in adults but not children. The aim of this study was to evaluate the safety, toleran...

background and objectives: sarcopenia is explained as age-related reduction in muscle mass and performance. some of the most important risk factors for sarcopenia include age, malnutrition, and sedentary life style. the aim of this study was to investigate the association of food intake and physical activity with body composition, muscle strength and muscle function in post-menopausal women. ma...

BACKGROUND Lack of information regarding biochemical changes in women during labor and its outcomes on maternal and neonatal health still is an unanswered question. This study aims to explore the effectiveness of oral carbohydrate intake during labor on the duration of the active phase and other maternal and neonatal outcomes. METHODS A parallel prospective randomized controlled trial, conduc...

CONTEXT Sports nutrition experts recommend that team-sport athletes participating in intermittent high-intensity exercise for ≥1 hr consume 1-4 g carbohydrate/kg 1-4 hr before, 30-60 g carbohydrate/hr during, and 1-1.2 g carbohydrate/kg/hr and 20-25 g protein as soon as possible after exercise. The study objective was to compare observed vs. recommended macronutrient intake of competitive athle...

Background and Objectives: Sarcopenia is explained as age-related reduction in muscle mass and performance. Some of the most important risk factors for sarcopenia include age, malnutrition, and sedentary life style. The aim of this study was to investigate the association of food intake and physical activity with body composition, muscle strength and muscle function in post-menopausal women. ...

It has been reported that morphine causes a selective increase in the intake of dietary fat. Because we have noted considerable variability among rats in their preferences for carbohydrate and fat, we reasoned that the effect of morphine on diet selection may differ in fat-preferring vs. carbohydrate-preferring rats. Male Sprague-Dawley rats were given ad lib access to separate sources of carbo...

The appropriate proportions of macronutritional intake have been controversial in medical nutritional therapy for diabetes, and evidence of the effects of carbohydrate consumption on diabetes complications in prospective settings is sparse. We investigated the relationships between proportions of carbohydrate intake as the % of total energy and diabetes complications in a nationwide cohort of J...