Inhibitors of fatty acid amide hydrolase (FAAH) and anandamide (AEA) uptake, which limit the degradation of endogenous cannabinoids, have received interest as potential therapeutics for pain. There is also evidence that endogenous cannabinoids mediate the antinociceptive effects of opioids. Assays of pain-elicited and pain-suppressed behavior have been used to differentiate the effects of drugs...

statement of the problem in iran and most countries temporomandibular disorders (tmds) are part of the education curriculum of general dentistry. most patients with these disorders are first referred to dentists. therefore, awareness of general dentists’ knowledge in this field is very important purpose the aim of this study was to evaluate knowledge and beliefs of general dental practitioners ...

objective: chronic pain is a common medical illnesses . purpose of this study is investigating the effectiveness of combination of cognitive behavior therapy and cognitive emotion regulation strategies on mindfulness, resiliency and quality of life in patients with chronic pain in tehran.   methods: 2 patients with chronic pain were selected through convenience sampling and answered to these qu...

UNLABELLED Cognitive-behavioral therapy (CBT) is effective in reducing the frequency and intensity of chronic pain in adolescents. However, CBT seems not to be considered acceptable by all adolescents. The main aim of our study was therefore to evaluate the effects of guided Internet-delivered self-help for adolescents with chronic pain. Adolescents (N = 69) were assessed on the outcome measure...