introduction: cholinergic systems are involved in learning and memory. scopolamine, a muscarinic acetylcholine receptor antagonist, is used as a standard/ reference drug for inducing cognitive deficits in healthy humans and animals. the purpose of this study was to evaluate the effects of scopolamine on avoidance memory and number of neurons in rat’s hippocampus. . methods: thirty five male alb...

OBJECTIVE This study aims to apply the virtual radial arm maze (VRAM) task to find spatial working memory and reference memory impairments in patients of amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD). Spatial memory functions between aMCI converters and nonconverters are also compared using VRAM results. METHODS We assessed the spatial memory in 20 normal controls, 20...

A 16kb lTlC FeRAM testchip is designed and fabricated in a 0.35pm FeRAM process. The testchip uses a reference generation scheme that balances fatigue evenly between memory cells and reference cells, hence providing the lTlC cell with 2T2C robustness to fatigue. The testchip achieves an access time of 6211s at 3V. Introduction Reference generation is an essential component of lT lC Ferroelectri...

Hypericum species are known to be used in traditional therapies. H. scabrum L. is one of the Hypericum species distributed in Turkey. In this study, we evaluated the effects of Hypericum scabrum essential oil inhalation on spatial memory in scopolamine-induced amnesic rats. The essential oil was characterized by GC-FID and GC-MS system. Male wistar rats were divided into 6 groups: control; scop...

Globally, it is estimated that nearly 10 million people sustain severe brain injuries leading to hospitalization and/or death every year. Amongst survivors, traumatic brain injury (TBI) results in a wide variety of physical, emotional and cognitive deficits. The most common cognitive deficit associated with TBI is memory loss, involving impairments in spatial reference and working memory. Howev...