recent studies have provided evidence that common genetic variations could account for a proportion of leukemia in adult or children. to evaluate the contribution of candidate gene association studies to the understanding of genetic susceptibility to acute lymphoblastic leukemia we conducted a systematic review from published studies. the polymorphisms of genes encoding carcinogen-metabolizing ...

background: to conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy for anxiety disorders. materials and methods: studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. case studies (with less than 4 cases) and single case designed studies were excluded. a comprehensive literature ...

conclusions the results of this review showed that the number of studies on the use of complementary medicine in leukemia patients is very limited (especially in iran), and it can be the subject of numerous studies in the future. results the overall results showed that few studies have been conducted on the use of exercise, massage therapy, music therapy, acupressure, and healing touch in patie...

BACKGROUND Meta-analysis of randomized controlled trials (RCTs) is usually based on trials where patients are randomized individually into two different, parallel, treatment groups. This paper concentrates on RCTs of a different design-two-period, two-treatment cross-over trials. METHODS The characteristics of these trials are outlined, with detailed examples of methods for analysis for both ...

Findings on the association between television (TV) viewing and all-cause mortality in epidemiologic studies have been inconsistent. Therefore, we conducted a meta-analysis of data from prospective cohort studies to quantify this association. Relevant articles were identified by searching MEDLINE (PubMed; National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, th...

Background: In 40-80% of children undergoing chemotherapy, oral mucositis is an acute complication which imposes significant financial and physical burdens on patients. In this article, a systematic review of published studies is conducted to investigate the role of nursing intervention in reducing oral mucositis. Materials and methods: This systematic review investigated, critically appraised...

Translation studies (TS), as a young (inter)discipline, has partly relied on metadiscussions, critical assessments of its literature, and compilation of bibliographies to deal with certain problems of its youth, such as polarity and fragmentation. While the current status of TS shows general maturity, there are still young areas of inquiry in the discipline that are faced with similar issues. T...

in this review, we aim to examine the effect of extrinsic and intrinsic factors on spermatogenesis process taking into account a complex signaling pathway. primarily, it is suggested that retinoic acid (ra) has a vital function in spermatogenesis process and it is considered to be essential for completion of spermatogonia into mature spermatozoa. in the present review, the key effects of retino...