نتایج جستجو برای: رنگبری tcf
تعداد نتایج: 2253 فیلتر نتایج به سال:
We investigated the relationship among ERK signaling, histone modifications, and transcription factor activity, focusing on the ERK-regulated ternary complex factor family of SRF partner proteins. In MEFs, activation of ERK by TPA stimulation induced a common pattern of H3K9acS10ph, H4K16ac, H3K27ac, H3K9acK14ac, and H3K4me3 at hundreds of transcription start site (TSS) regions and remote regul...
The transactivation of TCF target genes induced by Wnt pathway mutations constitutes the primary transforming event in colorectal cancer (CRC). We show that disruption of beta-catenin/TCF-4 activity in CRC cells induces a rapid G1 arrest and blocks a genetic program that is physiologically active in the proliferative compartment of colon crypts. Coincidently, an intestinal differentiation progr...
Flow cytometric and immunocytochemical analyses of murine fetal thymus (FT) cells with antibodies to various surface markers and transcription factors reveal that the synthesis of TCF-1 and GATA-3 protein begins simultaneously in a fraction of the most immature population of FT cells, which have the phenotype of CD4-CD8-CD44+CD25-. No TCF-1-producing cells is found in the fetal liver (FL). In C...
در این تحقیق، رنگبری پساب رنگی نساجی با استفاده از فرآیند فوتوفنتون مورد مطالعه قرار گرفت. رنگزای اسید آبی 92 به عنوان رنگزای آزوی اسیدی استفاده شد. عوامل مؤثر بر رنگبری در فرآیند فوتوفنتون مانند غلظت یون فرو، غلظت رنگزا و نمکهای سدیم (استات، کربنات، نیترات و بیکربنات) بررسی شدند. حداکثر غلظت آهن استفاده شده برابر با مقدار مجاز آهن در پساب در نظر گرفته شد. افزایش غلظت رنگزا و وجود آنیونهای اس...
Beta-catenin is the vertebrate homolog of the Drosophila segment polarity gene Armadillo and plays roles in both cell-cell adhesion and transduction of the Wnt signaling cascade. Recently, members of the Lef/Tcf transcription factor family have been identified as protein partners of beta-catenin, explaining how beta-catenin alters gene expression. Here we report that in T cells, Tcf-1 also beco...
PURPOSE Aberrantly activated Wnt/β-catenin signaling is important in hepatocellular carcinoma (HCC) development. Downstream gene expressions involving the Wnt/β-catenin cascade occur through T-cell factor (TCF) proteins. Here, we show the oncogenic potential of human TCF-4 isoforms based on the expression of a single conserved SxxSS motif. METHODS We investigated the TCF-4J and K isoform pair...
This paper presented a regrasp planning method to eliminate grasp uncertainty while considering the geometric constraints of fixture. The automatically finds Stable Placement Poses (SPPs) an object on Triangular Corner Fixture (TCF), elevates from its SPPs dropping poses and Deterministic Dropping (DDPs), builds graphs by using SPP-DDP pairs their associated configurations, searches graph find ...
در این پژوهش توانایی رنگبری رنگ آزوی بتا نفتول نارنجی توسط باکتری نمک دوست (halomonaz strain gb) و اثر فاکتور غلظت، ph و دما بر رنگبری بررسی می شود. با استفاده از ثابت نگهداشتن یک عامل و تغییر عوامل دیگر شرایط بهینه رنگبری، حاصل می شود. بالاترین درصد رنگبری 88% است که درغلظت ppm 40 و دمای c˚38 و 9=ph، پس از 6 روز گرماگذاری به دست آمد. غلظت در محدوده وسیع 15-ppm 125 بررسی شد و به همین دلیل توانا...
Initial studies have established expression of low-density lipoprotein (LDL) receptor-related protein 6 (LRP6) in vascular smooth muscle cells (VSMCs). We hypothesized that LRP6 is a critical mediator governing the regulation of the canonical Wnt/beta-catenin/T cell factor 4 (Tcf-4) cascade in the vasculature. This hypothesis was based on our previous work demonstrating a role for the beta-cate...
Previously, we reported the isolation of cDNA clones representing four alternative splice forms of TCF-1, a T-cell-specific transcription factor. In the present study, Western blotting (immunoblotting) yielded a multitude of TCF-1 proteins ranging from 25-55 kDa, a pattern not simply explained from the known splice alternatives. Subsequent cDNA cloning, PCR amplification, and analysis by rapid ...
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