hyperglycemia and gestational diabetes mellitus are complications of pregnancy. both mothers and newborns are typically at increased risk for complications. this study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance.in this clinical trial 44 pregnant women with imp...

Purpose: The aim of this study was to compare biochemical tests, body composition and anthropometric parameters in Nonalcoholic Fatty Liver Disease (NAFLD) patients before and after Ramadan fasting. Methods: fifty NAFLD patients including 33 males and 17 females aged 18-65 year, were recruited. Subjects attended after diagnosis based on  ultrasound imaging, with at least 10 hour fasting, before...

BACKGROUND Musculoskeletal disorders are very common among the diabetic patients and frozen shoulder is one of the disabling conditions. The present study was conducted to compare the serum triglyceride level among the patients of type 2 diabetic presented with and without frozen shoulder. METHODOLOGY This case control study was conducted from January 2008 to December 2009, in the department ...

Background The octanoylated peptide ghrelin stimulates growth hormone (GH) secretion during severe calorie restriction in mice, which preserves fasting blood sugar after body fat has been depleted. Genetic deletion of ghrelin-O-acyltransferase (GOAT, which octanoylates ghrelin) renders mice ghrelin-deficient and abrogates the normal rise in GH after several days of calorie restriction, resultin...

Target blood sugar levels in diabetes are achieved through manipulation of diet, exercise and medication. A change in any one of these three things can skew blood sugar levels and create complications associated with hyperglycemia or hypoglycemia. Fasting during the month of Ramadan is a religious activity that devout Muslims practice whether they are diabetic or not. Since such fasting involve...

Prior studies with carbonic anhydrase (CA) inhibitors implicated mitochondrial CA in ureagenesis and gluconeogenesis. Subsequent studies identified two mitochondrial CAs. To distinguish the contribution of each enzyme, we studied the effects of targeted disruption of the murine CA genes, called Car5A and Car5B. The Car5A mutation had several deleterious consequences. Car5A null mice were smalle...

objective: polycystic ovary syndrome (pcos) is one of the most common endocrine disorders in women. metformin is a biguanide commonly used to improve pcos symptoms. effect of metformin on the levels of serum homocysteine (hcy) in pcos women is unclear. the aim of this study is evaluating the effect of metformin administration on serum hcy levels and metabolic parameters of pcos patients. materi...

The effect of different periods of fasting on oral glucose tolerance was investigated in 33 subjects. It was found that glucose tolerance deteriorated as the fasting period became shorter. This effect was seen almost exclusively in subjects over 40 years of age. Only the fasting blood sugar was affected by the duration of the pretest fast in younger subjects.