Seizure is a rare but documented adverse event associated with ampicillin, which one of the most commonly used antibiotics in pediatrics. We report case 4-month-old male infant Haemophilus influenzae type A meningitis that experienced recurrent tonic-clonic seizures, possibly secondary to ampicillin treatment. After administration was withdrawn and antiepileptic agents were administered, seizur...

Introduction: Epilepsy is a common central nervous system (CNS) disorder characterized by seizures resulting from episodic neuronal discharges. The incidence of toxicity and refractoriness has compromised the clinical efficacy of the drugs currently used for the treatment of convulsions. Thus, there is a need to search for new medicines from plant origin that are readily available and safer for...

Background: Neonatal seizures can have many causes. Determining the underlying cause of neonatal seizures is very important in determining the prognosis, outcome, and treatment strategies. In this study, we have evaluated the frequency of Magnetic resonance imaging (MRI) findings in neonates younger than 6 months who had been referred to Shiraz Namazi hospital with seizures to determine the pre...

Background: Seizure is a chronic neurological disease that may have non-neurological origins such as astrocytes and microglia. Objective: The aim of this study was to investigate the effect of alone and co-administration of cabergoline and levetiracetam on the histological and stereological structure of the cerebral cortex, hippocampus and cerebellum following chronic seizures in rat. Methods...

Objective: To compare the emotional structure and coping strategies in patients with psychogenic non epileptic seizures, epilepsy and control group. Methods: Among patients with complaining of epilepsy attacks that referred to clinic of Imam Reza (Peace be upon him) in Shiraz, 30 patients with psychogenic non epileptic seizures and 30 patients with epilepsy were selected .A total of 30 patients...

Neurological effects of Valeriana officinalis have been recognized for many years. In this study, the anticonvulsant activity of methanolic extract of the plant were investigated in mice. Picrotoxin with doses of 6 and 12.5 mg/kg were used for induction of seizures. The effects of different doses of methanolic extract of the plant on the variation of beginning time of seizures, the incidence of...

Background Febrile seizure is the most common seizure disorders. Febrile seizure is divided into two groups of simple and complex seizures.  The aim of this epidemiological study was to assess the risk factors involved in the incidence of febrile seizures between the children referred to Besat hospital in the city of Sanandaj (Iran). Materials and Methods The present paper is a cross-sectional...

objective neonates, for many reasons, are at particular risk for the development of seizures, which are a strong predictor of later morbidity and mortality in infants. we undertook this study to determine the incidence, etiologic distribution and neonatal seizure type in neonates with hospital admission over a period of 4 years. materials and methods this, a retrospective study of newborns admi...

background: poisoning with non-barbiturate anti-epileptics (carbamazepine, sodium valproate and phenytoin) shows a growing trend. the objective of this study was to investigate clinical manifestations of poisoned patients with these medications. methods: this prospective study was conducted in the shiraz shoushtari hospital during a two-year period from 2010 to 2012. poisoning was confirmed acc...

objective: curcumin is a major constituent of turmeric and has many biological functions such as anticancer and anti-inflammatory effects. the present study was conducted to investigate the effects of curcumin and diazepam in separate and combined treatments on penicillin-induced seizures in rats. materials and methods: in urethane-anesthetized rats, epileptiform activity was induced by intraco...