In general, joints are assumed without clearance in the dynamic analysis of multi-body echanical systems. When joint clearance is considered, the mechanism obtains two uncontrollable degrees of freedom and hence the dynamic response considerably changes. The joints’ clearances are the main sources of vibrations and noise due to the impact of the coupling parts in the joints. Therefore, the syst...

BAR domains are highly conserved protein domains participating in a diversity of cellular processes that involve membrane remodeling. The mechanisms underlying such remodeling are debated. For the relatively well-studied case of amphiphysin N-BAR domain, one suggested mechanism involves scaffolding, i.e., binding of a negatively charged membrane to the protein's positively charged curved surfac...

Four-bar linkage mechanisms produced by many designers of knee joints for trans-femoral prostheses can provide knee rotation to permit walking only. In Afro-Asian countries people are accustomed to a squatting posture in their daily activities. A six-bar linkage knee-ankle mechanism trans-femoral prosthesis is described which was developed and fitted to an amputee. The motion patterns of the an...

Currently, rehabilitation systems with closed kinematic chain mechanisms are low-cost alternatives for treatment and health care. In designing these systems, the dimensional synthesis is commonly stated as a constrained optimization problem to achieve repetitive movements, metaheuristic algorithms problems promising methods searching solutions in complex search space. The Constraint Handling Te...

A hybrid approach of combining Taguchi method, principal component analysis and fuzzy logic for the tolerance design of a dual-purpose six-bar mechanism is proposed. The approach is to firstly use the Taguchi orthogonal array to carry out experiments for calculating the S/N ratios of the positional errors to the angular error of the dual-purpose six-bar mechanism. The principal component analys...

This document describes the design and construction of a mechanical device that allows subject with ectrodactyly to perform power grip. For this purpose, coupled bar mechanism for emulation finger is presented, system allows, from single movement, large diameter grip, considering variables obtained anthropometric goniometric measurement techniques. complemented by kinematic static analysis, in ...