The aim of the study was to report the diagnostic performance of total prostate-specific antigen (tPSA) and free prostate-specific antigen ratio (%fPSA). The diagnostic performances of tPSA and %fPSA were evaluated in 3 4 men by ROC curves, sensitivity, specificity and diagnostic odds ratio calculations. One hundred and sixty-two patients were diagnosed as prostate cancer (PCa) and 202 as norma...

The detrimental effect of chronic chromium (Cr) exposure on the prostate has never been studied. Here, we report the prostate specific antigen (PSA) changes in occupational chromate exposed workers. In this study, eighty six male occupational chromate exposed workers and forty five age-matched controls were recruited. The concentration of Cr in urine (U-Cr), serum total PSA (tPSA), free PSA (fP...

OBJECTIVES All studies investigating the elimination kinetics of serum total (tPSA) and free (fPSA) prostate-specific antigen (PSA) were carried out in men undergoing radical prostatectomy. Radical prostatectomy itself could, however, have a major influence on the serum concentration of these tumor markers (e.g., perioperative fluid shift or blood loss). The purpose of our study was to determin...

BACKGROUND The aim of our study was to identify the optimal predictor of prostate cancer among several prostate-specific antigen (PSA) derivatives in repeat prostate biopsy. METHODS We retrospectively assessed the repeat prostate biopsy specimens, obtained between 1999 and 2008, of 212 patients with a total PSA (tPSA) of 4-10 ng/ml and normal digital rectal examination. Using a receiver opera...

In this paper, a technique to generate expander graphs using Cellular Automata (CA) has been presented. The special class of CA, known as the Two Predecessor Single Attractor Cellular Automata (TPSA CA) has been characterized. It has been shown that the expander graphs built using the TPSA-CA are promising and lead to the development of strong one-way functions. The paper proposes an efficient ...

PURPOSE To examine the effectiveness of serum free-to-total prostate specific antigen ratio (%fPSA) for the detection of prostate cancer (PCa) in men with different serum total PSA (tPSA) categories. MATERIALS AND METHODS From January 2010 to December 2013, a total of 225 patients with lower urinary tract symptoms (LUTS) underwent tPSA and %fPSA measurements. Histological examination with cal...

PURPOSE To evaluate the natural background of prostate cancer in Iran a large population-based study of screening using total prostate-specific antigen (tPSA) and per cent free PSA (fPSA) as the initial test was performed. MATERIALS AND METHODS For 9 years (1996 to 2004) in Tehran, Iran, 3670 Iranian men older than 40 years were mass checked by PSA-based screening. They were invited to have a...