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Background With the availability of multiple Jak inhibitors (JAKi) for treatment, patients with RA who have had inadequate response to conventional therapies, including biologics, can now achieve favorable outcomes such as remission and low disease activity. However, it is also true that no single JAKi therapy effective all RA. Some treatment guidelines recommend a switch strategy from current ...
abstract part one: the electrode oxidation potentials of a series of eighteen n-hydroxy compounds in aqueous solution were calculated based on a proper thermodynamic cycle. the dft method at the level of b3lyp-6-31g(d,p) was used to calculate the gas-phase free energy differences ,and the polarizable continuum model (pcm) was applied to describe the solvent and its interaction with n-hydroxy ...
Background: Spermatozoa are germ cells that have a pivotal role at fertilisation. Infertility is a problem with a large magnitude. Sperm damages are one of the factors that cause infertility. Reactive oxygen species (ROS) like hydrogen peroxide (H2O2), superoxide anion (O2−U) or molecules and/or hydroxyl radical (UOH) affect both male and female gametes. Cyclosporine A (CsA), a neutral lipophil...
the main purpose of the present study was to investigate the relationship between listening proficiency and metacognitive listening strategies awareness among low, mid, and highly self-regulated students. three hundred and seventy one efl students participated in this study (all grade 3 and 4 high-school students who were studying in khansar in academic year 1391-92). to gather the data, three ...
nowadays, air pollution is a global problem that has had significant growth by technology development, population growth andindustrial development. industrial development brought natural resources deterioration, more manufacturing products, and more environmental pollutants. if pollutant won’t be controlled, human-being and wildlife will face the critical risks. significant release and critical...
cohesion is an indispensable linguistic feature in discourse analysis. lexicald such a differe cohesion and conjunction in particular as two crucial elements to textual cohesion and comprehension has been the focus of a wide range of studies up to now. yet the relationship between the open register and cohesive devices has not been thoroughly investigated in discourse studies. this study concen...
the present study aimed at investigating the relationship between iranian efl teachers’ classroom management orientations and their teaching styles. additionally, the difference between male and female teachers’ teaching styles and classroom management orientations and their relationship with experience and age were explored. three hundred efl teachers filled in attitudes and beliefs on classro...
Abstract Background Giant hiatus hernias (GHH), defined as more than 30% of the stomach herniating into chest cavity accounts for 5%-10% all hernias. GHH repair is undertaken electively in symptomatic patients, to prevent complications such volvulus with resultant mortality. Advances laparoscopy and perioperative care have reduced risk operation, improvement quality life (QoL) has become an imp...
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