Colon cancer represents a major public health issue. The aim of the SUDCAN collaborative study was to compare the net survival from colon cancer between six European Latin countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) and provide trends in net survival and dynamics of the excess mortality rates up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 dat...

Generalized Cross Validation (GCV) is a popular approach to determining the regularization parameter in Tikhonov regularization. The regularization parameter is chosen by minimizing an expression, which is easy to evaluate for small-scale problems, but prohibitively expensive to compute for large-scale ones. This paper describes a novel method, based on Gauss-type quadrature, for determining up...

INTRODUCTION colorectal cancer is one of the most common malignancies in developed countries. Data on specific and 10-year survival are scarce. This study analyzes overall and disease-specific survival for patients with colorectal cancer and assesses the value of clinical factors on disease-specific survival. METHODS a retrospective cohort study of newly diagnosed invasive colorectal cancer c...

Policymakers need to know whether prediction is possible and if so whether any proposed forecasting method will provide forecasts that are substantively more accurate than those from the relevant benchmark method. Inspection of global temperature data suggests that it is subject to irregular variations on all relevant time scales and that variations during the late 1900s were not unusual. In su...

THE AIM To determine the incidence of perinatal mortality, as well as the frequency of premature deliveries. METHODS We analyzed the data of birth protocol at the Clinics for Gynecology and Obstetrition at the University Clinical Centre in Tuzla in period 1992-2006. RESULTS Perinatal mortality gradually declines in the period of 1992-2000. The decline owns mostly to early neonatal mortality...