Overview Garlic’s current principal medicinal uses are to prevent and treat cardiovascular disease by lowering blood pressure and cholesterol, as an antimicrobial, and as a preventive agent for cancer. The active constituents are several complex sulfur-containing compounds that are rapidly absorbed, transformed and metabolized. Pooled data from numerous randomized trials suggest that garlic low...

We tested a mixture of Tridax procumbens, known for its direct action against Leishmania mexicana, and Allium sativum, known for its immunomodulatory effect, as an alternative to treat cutaneous leishmaniasis. Acute oral toxicity was tested with the Up-and-Down Procedure (UDP) using a group of healthy mice administered with either T. procumbens or A. sativum extracts and compared with a control...

objective(s): garlic (allium sativum l. family liliaceae) is well known in iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. research in recent decades has shown widespread pharmacological effects of a. sativum and its organosulfur compounds especially allicin. studies carried out on the chemical composition of the plant show that the most importan...

Results Thirty-two studies met the inclusion criteria. Clinical studies were divided into three categories: survey studies (n=11), safety studies (n= 8), and efficacy studies (n= 13). Six studies were randomized controlled trials. The most common herbs studied were St. John’s wort (Hypericum perforatum L.) (n=3), garlic (Allium sativum L.) extract (n=2), and senna (Cassia senna L.) (n=2). Studi...

Garlic (Allium sativum L., Alliaceae), Persian shallot (Allium ascalonicum L., Alliaceae ) and Sage (Salvia officinalis L., Lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as antidiabetic herbal medicines in Iran. In this study, diabetes was induced by subcutaneous injection of alloxan monohydrate (100 mg kg(-1)) to male Wistar rats. Antidiabetic effects...

Plants of the Allium genus, for example garlic and onion, are relatively odourless as long as they are intact. But if they are crushed or cut, a bunch of strong aromas are released. This is the result of a reaction between the enzyme alliinase and its substrates, alk(en)yl cysteine derivatives, probably as a defence against pests (Ellmore et al., 1994; Ankri et al., 1999). This occurs after cel...

The genus Allium comprises about 700 species. Several of them are important vegetables, spices and medicinal plants. The most important crop species are onion and shallot, Allium cepa L., garlic, Allium sativum L., leek, Allium ampeloprasum L. s.l., bunching onion, A. fistulosum L., chives, A. schoenoprasum L., Chinese chives, A. tuberosum Rottl. ex Spr., and rakkyo, A. chinense G. Don. Many ot...

BACKGROUND Allium sativum L. (A.S.) "garlic", one of the most interesting medicinal plants, has been suggested to contain compounds that could be beneficial in numerous pathological situations including cancer. In this work, we aimed to assess the immunomodulatory effect of A.S. preparation on human peripheral blood mononuclear cells from healthy individuals. METHODS Nontoxic doses of A.S. we...