Natural History Statistics Older statistics estimate that in the United States, acute pulmonary thromboembolism afflicts 500 000 to 600 000 persons annually and is either a primary or secondary cause of death in 150 000 to 200 000 of these individuals.1,2 Extrapolation of a population-based study from data accumulated in 1985 through 1986 in Worcester, Mass, suggests that each year there are '1...

Background: Sublingual immunotherapy with grass allergen tablets may be the future treatment for grass pollen allergy because it reduces symptoms and medication use, improves quality of life and is easy to use. Rhinoconjunctivitis and asthma co-exist and we aimed to fi nd a safe dose range of a self-administered grass allergen tablet (ALK Abello A/S) in patients suffering from rhinoconjunctivit...

Heroin is an illegal drug and monitoring heroin use is important in rehabilitation, pain management services, and workplace employment testing. In humans, heroin is rapidly converted to 6-acetylmorphine (6AM), which is quickly hydrolyzed to morphine. Morphine glucuronide is the major metabolite of heroin in urine (1 ). However, 6AM is a unique metabolite of heroin and is considered the definiti...

Maple syrup urine disease (MSUD) is an autosomal recessive condition with an incidence of approximately 1 in 150 000 live births with a higher incidence amongst children from consanguineous relationships [1]. It is caused by an enzymatic deficiency with reduction in oxidative decarboxylation of branched-chain amino acids (BCAA) (leucine, isoleucine and valine) resulting in elevated levels and t...

Maple syrup urine disease (MSUD) is an autosomal recessive condition with an incidence of approximately 1 in 150 000 live births with a higher incidence amongst children from consanguineous relationships [1]. It is caused by an enzymatic deficiency with reduction in oxidative decarboxylation of branched-chain amino acids (BCAA) (leucine, isoleucine and valine) resulting in elevated levels and t...

(sinα)/α [113]. 0 [210]. 1 [222]. 1/π [188, 189]. 1/π [217, 189]. 10, 000 [49]. 10, 000, 000 [134]. 16 [197]. 2 [52, 55]. 2 + 2 [209]. 2, 000 [35]. 2, 576, 980, 370, 000 [211]. 29, 360, 000 [98]. 2H2 [221]. b [176]. e [99, 93, 56, 34, 111, 28, 35, 36, 209, 12, 54]. e−(π/2) = i [13]. GL(n, Z) [96]. n [141, 96, 133]. φ [187, 194]. π [228, 183, 84, 135, 97, 136, 169, 227, 31, 98, 99, 24, 20, 168, ...