The metabolic fate of tacrine [1,2,3,4-tetrahydro-9-acridinamine monohydrochloride monohydrate (THA)] was examined in rats, dogs, and humans. After administration of single oral doses of [14C]THA to rats, dogs, and humans, drug-derived material was well absorbed, with urinary excretion being the predominant route of radiolabel elimination. Metabolic profiling of plasma and urine from rats, dogs...

Purpose: Developmental dysplasia of the hip (DDH) increases the risk of secondary degenerative changes and subsequent total hip arthroplasty. The postoperative quality of life in patients with DDH who have been born and grown with this disability and adapted to it during the life, is one of the most challenging issues. This study aimed to compare the quality of life of patients with DDH before ...

(1) Background: Metal-on-metal (MoM) total hip arthroplasty (THA) and resurfacing (HRA) was presumed to provide superior functional outcomes compared metal-on-polyethylene (MoP) THA. (2) Methods: We muscle mass, power, step test asymmetry, patient-reported between MoM THA/HRA MoP A of 51 THA/HRAs 23 THAs participated in the cross-sectional study at a mean 6.5 (2.4–12.5) years postoperatively. M...

BACKGROUND Total hip arthroplasty (THA) is an increasingly common procedure among elderly individuals. Although conversion THA is currently bundled in a diagnosis related group (DRG) with primary THA, no study has identified whether patients undergoing conversion THA better resemble patients undergoing primary THA or revision THA. The American College of Surgeons National Surgical Quality Impro...

ABSTRACT-Several herbicides are registered for selective weed control in sugar beet; however, no single chemical herbicide can control all weeds in beet fields. Frequently, two or more herbicides may have to be combined sequentially or as tank mixed to achieve adequate broad-spectrum weed control. In order to evaluate the effects of some combinations of broadleaf herbicides on sugar beet yield ...

Abstract Introduction We determined the association between frailty and 30-day mortality following total hip knee arthroplasty (THA/TKA) due to osteoarthritis also impact of THA/TKA on compared a control population. Method used linked primary secondary care data Office for National Statistics data. Frailty was assessed using electronic index categorised as fit, mild, moderate, severe frailty. T...

Root tips from the marsh grass Spartina alterniflora, collected from areas of high and low pore-water sulfide, exhibited a substantial capacity to catalyze sulfide oxidation, as determined by closed-chamber respirometry. A large proportion of this catalysis was apparently nonenzymatic and was higher in roots of plants from the high-sulfide versus the low-sulfide site. Activity exhibiting charac...