The chemical structure of a drug determines its physicochemical properties, further determines its ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can regulate the pharmacological activity of drug molecules by modifying their structure. Ring systems and functional groups are important components of a drug. The proportion of non-hydrocarbon atoms amon...

PURPOSE To investigate the effects of divided attention on conventional automated perimetry (CAP) and luminance size threshold perimetry (LSTP). METHODS Ten healthy subjects, ages 27 to 65, with two perimetry types (CAP and LSTP) were tested in random order. At a later session, these tests were given with a mental workload to simulate the effect of anxiety or distraction on subjects performin...

background welding is defined as linking two metals with a local conjunction in sufficient thermal, pressing and metallurgical condition. there are several methods for linking two metals in welding. objectives welding is one of the professional jobs in iran, yet there have not been considerable studies on its harmful effects. the current study aimed to compare lung functional tests between weld...

Farm animals and their products have a longstanding and successful history of providing significant contributions to human nutrition, clothing, facilitation of labour, research, development and medicine and have thus been essential in improving life expectancy and human health. With the advent of transgenic technologies the potential of farm animals for improving human health is growing and man...

The purpose of this paper is to solve the seventh-order functional equation as follows:  --------------------------- Next, we study the stability of this type of functional equation. Clearly, the function ----------  holds in this type functional equation. Also, we prove Hyers-Ulam stability for this type functional equation in the β-Gaussian Banach space.  

abstract   background : although, different studies on end-to-side nerve repair, results are controversial. the importance of this method in case is unavailability of proximal nerve. in this method, donor nerves also remain intact and without injury. in compare to other classic procedures, end-to-side repair is not much time consuming and needs less dissection. overall, the previous studies in ...

background and aim: total hip replacement (thr) is done comprehensively all over the world. despite the effects of braces on control of thr complications , few studies have been performed on this subject. the purpose of this study was to evaluate immediate effect of hip abduction brace on mobility and functional balance of patients with thr.    materials and methods: eight men and nine women wi...

introduction sleepiness refers to drowsiness, feelings or strong will to sleep, and decreased functional outcomes. this study was conducted to determine the relationship between sleepiness, physical activity, and functional outcomes of sleep in iranian patients with type ii diabetes. materials and methods in this cross-sectional study 220 outpatients with type ii diabetes were selected through ...