Hesperidin is a flavonone glycoside found in sweet orange and is effectively used in treatment for pain and disease. Although it plays a big role in the pharmaceutical area, hesperidin has a poor water soluble property. β-cyclodextrin (β-CD), a macrocyclic host with hydrophobic cavity and hydrophilic outer surface is a common pharmaceutical application to enhance the solubility, stability, safe...

Reaction of 4,6‐bis(1‐hydrazonoethyl)benzene‐1,3‐diol with 3‐nitrobenzaldehyde gave the new bis (bidentate) hydrazone ligand; 4,6‐bis(3‐nitrobenzalen‐1‐yl)methylene)hydrazono)ethyl)benzene‐1,3‐diol (H 2 L; H BisBD). Binuclear Co (II), Ni and Cu (II) complexes general formula ([M BisBD(H O) x (EtOH) y ].nH O; M = Co, or Cu, 4 6, 0; n 1 0) have been successfully prepared. The structures BisBD its...

Fullerene chemistry is nowadays a well-established field of both theoretical and experimental investigations‎. This study considers the symmetry of small fullerenes cage C24 and C28‎. ‎Using PM3 program for C24 and C28 fullerenes, Oh and Td symmetry were confirmed, respectively‎. ‎ The mentioned algorithm to compute the automorphism group of these fullerenes with connectivity and geometry of th...

Malaria is a parasitic disease with limited chemotherapy options. Chemotherapy options are limited; moreover, drug resistant frequently occurs. The speed of drug development should be faster to overcome the emerging drug resistance. In the current study, a series of quinolone derivatives were subjected to quantitative structure activity relationship to identify the ideal physicochemical charact...

The interaction of ligands and their transition metal complexes with plasmid (pUC19 DNA) and calf Thymus DNA were investigated by UV spectroscopic studies and gel electrophoresis measurements. The interaction between ligand/metal complexes and DNA was carried out by increasing the concentration of DNA from 0 to 10 μl in UV spectroscopic study, while the concentration of DNA in gel electrophores...