Objective: To investigate the clinicopathological, therapeutic, and survival data on pediatric major salivary gland cancers. Materials Methods: National Cancer Database (NCDB) query from 2004 to 2018. Results: In total, 967 cases of individuals under age 21 were identified. Most cancers affected parotid (86%). Mucoepidermoid carcinoma (41.3%) acinic cell adenocarcinoma (33.6%) most common. Tumo...

Mucoepidermoid carcinoma of the maxillary sinus is a rare malignancy of the head and neck. The location of this tumour near vital structures and its large size at presentation makes surgical resection with negative margins challenging. In incurable cases, relief from symptoms such as epistaxis may be achieved with radiation therapy. We present a case of mucoepidermoid carcinoma of the maxillary...

BACKGROUND Improved survival seen in Acute Lymphoblastic Leukemia (ALL) cases has led to increased reports of second malignant neoplasms. CASE CHARACTERISTICS A 12-year-old female treated for ALL using UK ALL XI protocol nine years back presented with progressively increasing pre-auricular swelling. OBSERVATION Investigations revealed it to be a Mucoepidermoid carcinoma. MESSAGE Mucoepide...

Neoplasms of the major and minor salivary glands are morphologically and a clinically diverse group of neoplasms which lead the clinician to diagnostic and management challenges. This article aims to report a case of mucoepidermoid carcinoma in 83 - year - old woman who presented in the dermatology clinic with a tumour mass in the left auricular area. The patient complained of pain and abnormal...

Mucoepidermoid carcinoma of the trachea is a rare tumor. We report an 80-year-old male with mucoepidermoid carcinoma in the upper trachea with invasion of the isthmus of thyroid gland. The patient’s major symptom was dyspnea with coughing. Computed tomography scan showed a protruding mass into the trachea suspected of thyroid cancer. Ultrasonography also revealed the suspicion of an invasive th...

Malignant tumors of the paranasal sinus are uncommon, constituting less than 1% of all malignancies and 3% of all head and neck cancers. Nonsquamous cancers of the maxillary sinus are even rarer as is evident from the limited data available on the clinical characteristics and outcomes. Mucoepidermoid carcinoma accounts for 13% of all malignancies occurring in maxillary sinus. We report a rare c...

Introduction: Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary g...

INTRODUCTION Sclerosing mucoepidermoid carcinoma with eosinophilia is a rare morphological variant of thyroid carcinoma associated with Hashimoto's disease. To date, only three such tumors have been reported in the minor salivary glands. We describe the first case, to the best of our knowledge, of recurrent sclerosing mucoepidermoid carcinoma with eosinophilia in the minor salivary glands of th...