Loss of skeletal muscle mass and function (cachexia) is severe in patients with colorectal liver metastases because of the large increase in resting energy expenditure but remains understudied because of a lack of suitable preclinical models. Our aim was to characterize a novel preclinical model of cachexia in colorectal liver metastases. We tested the hypothesis that mice with colorectal liver...

Background: Biloma is a rare abnormal localized accumulation of bile out of biliary tree due to an injury. It has different non-specific clinical features and its diagnosis is based on clinical signs, radiologic findings and chemical analysis of aspirated liquid. Considering the non-specific clinical features, early diagnosis and treatment can have an effective role in the decrease of complicat...

background: peritoneal tuberculosis accounts 1-2% of all forms of tuberculosis. peritoneal tuberculosis is an important differential diagnosis for ovarian cancer in women with ascites, adnexal mass and elevated cancer antigen 125 (ca125) levels. we report a case of a 32- year -old woman with multiple miliary peritoneal deposits mimicking advanced ovarian carcinoma. case presentation: a 32-year-...

Background: Peritoneal tuberculosis accounts 1-2% of all forms of tuberculosis. Peritoneal tuberculosis is an important differential diagnosis for ovarian cancer in women with ascites, adnexal mass and elevated cancer antigen 125 (CA125) levels. We report a case of a 32- year -old woman with multiple miliary peritoneal deposits mimicking advanced ovarian carcinoma. Case Presentation: A 32-ye...

Objective(s): Weight gain and metabolic disturbances such as dyslipidemia, are frequent side effects of second-generation antipsychotics, including olanzapine. This study examined the metabolic effects of chronic olanzapine exposure. In addition, we investigated the hepatic fatty acid effects of olanzapine in female C57BL/6J mice fed a normal diet.Materials and Methods: Female C57BL/6J mice ora...

background: biloma is a rare abnormal localized accumulation of bile out of biliary tree due to an injury. it has different non-specific clinical features and its diagnosis is based on clinical signs, radiologic findings and chemical analysis of aspirated liquid. considering the non-specific clinical features, early diagnosis and treatment can have an effective role in the decrease of complicat...

Background: Type-2 diabetes is a risk factor for progressive non-alcoholic fatty liver disease and the majority of diabetic patients have blood lipid disorders, so they take statin drugs. Statins have the adverse effects such as liver dysfunction and increase in liver enzymes. The purpose of this study was to compare the liver enzymes in type 2 diabetic patients who are user and non-user of sta...

A 45-year-old woman presented with a headache and visual complaints. Brain MRI revealed a large mass in the right occipital cortex. The tumor was surgically removed and pathological examination showed papillary carcinoma originating from thyroid gland. She had a history of thyroid surgery 27 years ago indicating papillary thyroid cancer with central neck lymph node involvement followed by no ad...

conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...