نتایج جستجو برای: liver tissue
تعداد نتایج: 1174612 فیلتر نتایج به سال:
The histopathological effects of Linear Alkylbenzene Sulfonate on the gill, liver and kidney tissues of the Caspian kutum, Rutilus frisii kutum were studied. The fish were exposed to three sublethal concentrations of anionic detergent, Linear Alkylbenzene Sulfonate (LAS) for short term intervals (192 h). Gill, liver and kidney samples were collected after 192 h of exposure to LAS and lesions we...
Background: The aim of this study was to investigate the pretreatment effects of time courses of training and different doses of medication in multiple organs (liver and heart) of rats treated with doxorubicin (DOX). Methods: in this experimental study, Seventy-two Wistar male rats were randomly assigned to control and training groups with three subgroups: DOX 10mg/kg, DOX 20mg/kg and saline...
Abstract The proper functional interaction between different tissues represents a key component in systemic metabolic control. Indeed, disruption of endocrine inter-tissue communication is hallmark severe dysfunction obesity and diabetes. Here, we show that the FNDC4-GPR116, liver-white adipose tissue axis controls glucose homeostasis. We found liver primarily controlled circulating levels solu...
Background & Aims: Cyclophosphamide is an anticancer drug that, despite its many clinical applications, has toxic effects through production of free radicals on body. The aim of this study was to evaluate the protective effects of N-acetylcysteine in the liver tissue of rats treated with cyclophosphamide Materials & Methods: Twenty-one adult female Wistar rats were randomly divided into 3 grou...
Introduction: Thyroid hormones play an important role in normal function of liver and hyperthyroidism can cause liver dysfunction. Thyroid hormones affect nitric oxide (NO)-producing enzymes in liver. The aim of this study is to investigate effects of hyperthyroidism on protein levels of three isoforms of NO synthase (NOS) enzymes, including endothelial NOS (eNOS), inducible NOS (iNOS), and neu...
Background and Objective: Wheras renal ischemic-reperfusion injury increases lipid peroxidation level in the liver tissues, it decreases the antioxidant activity and antioxidant enzymes. Olive leaves are considered as significant sources of bioactive phenolic compounds with superior antioxidant capacity, anti-inflammatory and radical scavenging. Materials and Methods: In this study 50 male r...
Background and purpose: Cisplatin is used in chemotherapy for cancer patients. But, it has adverse effects on some organs, including the kidney and liver. P-coumaric acid is a polyphenolic substance with multiple biological properties. The present study aimed to investigate the effect of p-coumaric acid on renal and hepatic side effects of cisplatin. Materials and methods: This experimental st...
The histopathological effects of Linear Alkylbenzene Sulfonate on the gill, liver and kidney tissues of the Caspian kutum, Rutilus frisii kutum were studied. The fish were exposed to three sublethal concentrations of anionic detergent, Linear Alkylbenzene Sulfonate (LAS) for short term intervals (192 h). Gill, liver and kidney samples were collected after 192 h of exposure to LAS and lesions we...
Background: Cutaneous leishmaniasis is a common parasitic disease in Iran being mainly caused by Leishmania (L.) major. The aim of this study was to investigate the occurrence of apoptosis in the spleen and liver of female mice infected with L. major.Methods: BALB/c mice were randomly assigned into the control and experimental groups (ten mice per group). The experimental groups were subcutaneo...
Background and purpose: Induction of cellular senescence is indicative of new strategy to prevent abnormal proliferation of cancer cells. Doxorubicin (DOX) is gaining attention for its neoplasia suppressive and inhibitory properties, but its clinical utility is limited due to irreversible effects on non-target cells/tissues. In this way, nanoliposomal structures were developed in drug delivery ...
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