The aim of the therapy in open tibial fractures grade III was to cover the bone with soft tissue and achieve healed fracture without persistent infection. Open tibial fractures grade IIIC with massive soft tissue damage require combined orthopaedic, vascular and plastic-reconstructive procedures. Negative-pressure wound therapy (NPWT), used in two consecutive cases with open fracture grade IIIC...

background and aims. furcally-involved teeth present unique challenges to the success of periodontal therapy and influence treatment outcomes. this study aimed to assess to compare use of adm and connective tissue membrane in class ii furcation defect regeneration. materials and methods. 10 patient with 2 bilaterally class ii furcation defects in first and/or second maxilla or man-dibular molar...

Background: There are multiple methods for acceleration of bone healing. Bone marrow has been shown to contain osteoprogenitor cells. Objective: To determine the effect of percutaneous bone marrow injection on bone healing. Methods: 15 mature, 2-kg-weighing white New Zealand rabbits from both sexes were randomized into 3 groups: Group I: Only osteotomy of right radius was performed and a 5 mm b...

BACKGROUND It has been studied that the distribution of bone morphogenetic protein 2 is regular under bone defect situation. OBJECTIVE To observe the expression of bone morphogenetic protein 2 in rabbit radial defect site with different lengths. METHODS Forty-eight New Zealand rabbits were divided into two groups randomly. 0.5 cm bone defect and 3.0 cm bone defect were made by wire saw at t...

Osteoarthritis in the knees, which can be caused by meniscal defect, constitutes an increasingly common medical problem. Repair for massive meniscal defect remains a challenge owing to a lack of cell kinetics for the menisci precursors in knee joint. The synovium plays pivotal roles during the natural course of meniscal healing and contains mesenchymal stem cells (MSCs) with high chondrogenic p...