Prostate cancer is the second most common cancer in men worldwide, and the eighth leading cause of cancerrelated death. Globally, there are approximately 1,100,000 new cases and 300,000 mortalities every year, comprising nearly 4 percent of all cancer deaths. It is estimated that 1 in every 7 men will be diagnosed with the disease during his lifetime[1]. The most dangerous stage of prostate can...

the aim of the present paper is to define and study (ic)$lm$-fuzzytopological spaces, a generalization of (weakly) induced $lm$-fuzzytopological spaces. we discuss the basic properties of(ic)$lm$-fuzzy topological spaces, and introduce the notions ofinterior (ic)-fication and exterior (ic)-fication of $lm$-fuzzytopologies and prove that {bf iclm-ftop} (the category of(ic)$lm$-fuzzy topological ...

Various agents are able to stimulate the EGF receptor protein tyrosine kinase in the absence of ligand binding. To characterize their mechanism of action, we investigated their effects on the kinase activity of the intracellular domain of the EGF receptor (EGFR-IC). EGFR-IC (67 kDa) lacking the extracellular domain and transmembrane segment of the EGF receptor, but retaining kinase and autophos...

Polymeric alkylpyridinium salts (poly-APS) isolated from the Mediterranean marine sponge, Haliclona (Rhizoniera) sarai, effectively inhibit barnacle larva settlement and natural marine biofilm formation through a non-toxic and reversible mechanism. Potential use of poly-APS-like compounds as antifouling agents led to the chemical synthesis of monomeric and oligomeric 3-alkylpyridinium analogues...

The aim of the present paper is to define and study (IC)$LM$-fuzzytopological spaces, a generalization of (weakly) induced $LM$-fuzzytopological spaces. We discuss the basic properties of(IC)$LM$-fuzzy topological spaces, and introduce the notions ofinterior (IC)-fication and exterior (IC)-fication of $LM$-fuzzytopologies and prove that {bf ICLM-FTop} (the category of(IC)$LM$-fuzzy topological ...