Communication between cells pervades the development and physiology of metazoans. In animals, this process is carried out by a relatively small number of signaling pathways, each consisting of a chain of biochemical events through which extracellular stimuli control the behavior of target cells. One such signaling system is the Hedgehog pathway, which is crucial in embryogenesis and is implicat...

TOPIC: Tobacco Cessation and Prevention TYPE: Original Investigations PURPOSE: The stage at diagnosis is the single most important predictor of lung cancer outcome, making early detection utmost importance. National screening trial found significant benefit from with low dose Computed tomography (LDCT). Despite this, less than 4 % high-risk population get annual LDCT. Patients' attitudes toward...

Based on the practical experience of power grid planning, general characteristics and main problems receiving-end are summarized, ideas methods external receiving planning put forward. Combined with current situation, pattern supply demands a typical recipient network in China, this paper analysed reasonable scale receiving, proportion AC/DC transmitted infeed terminal location for long-term de...

The preoperative care of patients undergoing orthopedic surgery and treated with biologic agents is of great significance.Perioperative use of biologic agents could lead to such complications as infection and delayed postoperative woundhealing. This narrative review aimed to evaluate the current information on the use of biologic agents in patientsundergoing orthopedic surgery...

Background: Pomegranate seed oil and its main constituent, punicic acid, have been shown to decrease plasma glucose and have antioxidant activity. The objective of the present study was to examine the effects of pomegranate seed oil on rats with type 2 diabetes mellitus. Method: Six groups (n=8 each) of male Sprague-Dawley rats, comprising a control, a diabetic (induced by Streptozocin and Nico...

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