A quiet but profound revolution in theoretical framework, a paradigm shift, now has infused the consideration of therapies in autoimmune diseases and cancers, as exem-It is becoming accepted that a large set of antigenic determinants of the self have not induced self-tolerance (reviewed by Sercarz et al., 1993) and that these peptide determinants furnish target structures for autoimmune attack ...

INTRODUCTION Participation in early-phase HIV cure studies includes clinical risks with little to no likelihood of clinical benefit. Examining the willingness of people living with HIV to participate is important to guide study design and informed consent. Our study examined the overall willingness of people living with HIV to participate in HIV cure research in the US, focusing on perceived ri...

BACKGROUND The heat produced by provisional restoration materials may injure the dental pulp. This study measured and compared peak temperatures during polymerization of 5 materials used in the fabrication of provisional restorations. METHODS The tested materials were 2 self-curing resins (Integrity and Protemp) and 3 dual-cure resins (Iso-Temp, TCB Dual Cure and Provipont DC). A mould the si...

The study was carried out to evaluate and compare dentine margin microleakage of nano-filled resin composite restorations placed with a RMGIC using the co-cure technique and those placed with an ‘all-in-one’ self-etch DBA. In premolar teeth, that had to be extracted for orthodontic reasons, two proximal boxes with gingival margins placed in dentine were prepared. Restorations were inserted usin...

To investigate the bonding of tooth-colored indirect restorations to cervical dentin, shear bond strengths of bonded resin inlays to cervical dentin and mid-coronal dentin were investigated and compared. Indirectly fabricated composite inlays (Estenia) were cemented with a dual-cured resin cement (Panavia Fluoro Cement II) to either cervical or mid-coronal dentin. Resin cement was cured with or...