malaria is a major problem in tropical and sub-tropical countries, with high morbidity and mortality. splenectomy makes patients more susceptible to serious bacterial and parasitic infections. we report for the first time in iran a fatal case of plasmodium vivax malaria, confirmed by microscopic and molecu­lar (semi-nested multiplex pcr) tests in a patient who had undergone splenectomy due to h...

PURPOSE Single-port laparoscopic splenectomy has been performed sporadically. The aim of this study is to assess our experience with single-port laparoscopic splenectomy compared to conventional multiport laparoscopic surgery for the usual treatment modality for various kinds of splenic disease. METHODS Between October 2008 to February 2014, 29 patients underwent single-port laparoscopic sple...

OBJECTIVE Non-operative management of blunt splenic injury in adults has been applied increasingly at the end of the last century. Therefore, the lifelong risk of overwhelming post-splenectomy infection has been the major impetus for preservation of the spleen. However, the prevalence of posttraumatic infection after splenectomy in contrast to a conservative management is still unknown. Objecti...

The recent large decrease in splenectomy use for chronic immune thrombocytopenia (ITP) is partly due to still-unsolved questions about long-term safety. We performed the first single-center exposed/unexposed cohort study evaluating the long-term incidence of splenectomy complications in patients with primary ITP. Overall, 83 patients who underwent splenectomy more than 10 years ago (exposed) we...

Background: No evidence of the possibility to alter a constituent immune system without directly affecting one its associated components has been shown yet. Methods: A schematic model was developed in which two triggers, fasting and splenectomy, were studied for their ability affect expression cell membrane epitopes cytokine secret...

We present the case of a 34-year-old female patient with severe pulmonary hypertension diagnosed > 15 years after splenectomy to emphasize need monitor patients for development chronic thromboembolic (CTEPH). The lack screening tests this group patients, as in described case, resulted serious clinical condition at time diagnosis. Without specialized treatment, probability her survival 5 was onl...