Tumor markers are a group of molecules used to diagnose certain diseases, including cancer. These can alter cellular pathways, those associated with some anemias, by expressing or influencing mediators. The present study is based on data obtained from the PubMed database (1970–2019) using key words ‘tumor markers’, ’anemia’ and ‘iron’. We found that tumor affect hepcidin expression iron uptake ...

Monoclonal antibodies are used to detect serum antigens associated with specific malignancies. These tumor markers are most useful for monitoring response to therapy and detecting early relapse. With the exception of prostate-specific antigen (PSA), tumor markers do not have sufficient sensitivity or specificity for use in screening. Cancer antigen (CA) 27.29 most frequently is used to follow r...

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Background: Ramsar (Mazandran province) is known for its extremely high levels of natural background radiation. Although no excess cancer rate is reported in these areas by epidemiological studies, the study of tumor markers in the inhabitants of these areas may shed some light on the impact of high levels of background radiation on cancer induction. Materials and Methods: The level of backgrou...

littoral cell angioma is a splenic vascular tumor of splenic sinus lining cells that is considered benign in general. this report describes a case of littoral cell angioma with no malignant histological features. the lesion is composed of anastomosing vascular channels resembling splenic sinus; they are lined by endothelial cells which show mitotic activity very rare. immunohistochemically, the...