Effects of R[+]-8-([1-[3,4-dimethoxyphenyl]-2-hydroxyethyl]amino) -3,7-dihydro-7-[2-methoxyethyl]-1,3-dimethyl-1H-purine-2,6-dione (MKS-492), a reported type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, on antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats were investigated. 1) MKS-492 inhibited antigen-induce...

OBJECTIVES The in vitro activity of a new fluoroquinolone, ABT-492, was determined. METHODS MICs were compared with those of two beta-lactams, telithromycin, ciprofloxacin and four later generation fluoroquinolones. The effects of human serum and of inoculum concentration were also investigated. RESULTS MIC data indicate that ABT-492 has potent activity against Gram-positive organisms with ...

The Thirty Meter Telescope has 492 primary mirror segments, each incorporated into a Primary Segment Assembly (PSA), each of which in turn has three actuators that control piston, tip, and tilt, for a total of 1476 actuators. Each actuator has a servo loop that controls small motions (nanometers) and large motions (millimeters). Candidate actuators were designed and tested that fall into the ca...

data parallelism for a decision tree, 489–492 data set structure, 479–480 decision tree algorithm, 480–481 decision tree classification, 477–480 processes, 480–488 structure, 478–479 result parallelism for the decision tree, 492–495

one hundred female markhoz goats (42±5 kg) were used to investigate the ‘male effect’ on estrous synchronization and reproductive characteristics of female goat during the breeding season. this was carried out in three separate experiments. in the first experiment, forty female goats were used in 4 groups with different distance from the male goats (i.e. source of pheromone secretion); a1 (1 me...