essential hypertension (eh) accounts for 90-95% of hypertension cases. eh, as a progressive cardiovascular syndrome arising from complex and interrelated etiologies, results from combined and interactive effects of genetic and environmental factors. the objective was to investigate the ace i/d and gnb3 c825t polymorphisms and both genotypes combined with seeking gene-gene interactions to furthe...

objective(s): foxp3 gene is an x-linked gene that encodes foxp3 protein, an essential transcription factor in cd4+cd25+foxp3+ regulatory t (treg) cells.  we aimed, in the present study, to investigate the association of two foxp3 polymorphisms, -2383 c/t (rs3761549) and ivs9+459 t/c (rs2280883), with lung cancer. materials and methods:  in a case-control study we analyzed genotypes and alleles ...

present investigation was carried out to identify dna polymorphism of il-2rγ and chb6 genes. sixty five birds belonging to the indigenous chicken of himachal pradesh were utilized. good quality dna samples were subjected to pcr-rflp analysis using chicken specific primers. overnight restriction enzyme digestion was carried out at 37°c with iu hph i and pvu ii for il-2rγ and chb6 genes, respecti...

canine distemper virus (cdv) creates a very contagious viral multi-systemic canine distemper (cd) disease that affects most species of carnivora order. the virus is genetically heterogeneous, particularly in section of the hemagglutinin (h) gene. sequence analysis of the h gene can be useful to investigate distinction of various lineages related to geographical distribution and cdv molecular ep...

  Genetic typing methods of T. gondii strains have been extensively perfected in recent years. From a technical point of view, many tools usable for genetic studied on single-copy loci have been used: RFLP, PCR-RFLP, sequencing, RAPD-PCR and isoenzyme analysis. We described the cloning and sequence analysis of the gene which encodes the major surface antigen (SAG1 or P30) of T. gondii. SAG1 is ...

background: using primary tumor gene expression has been shown to have the ability of finding metastasis-driving gene markers for the prediction of breast cancer recurrence (bcr). however, there are some difficulties associated with the analysis of microarray data which led to poor predictive power and inconsistency of the previously introduced gene signatures. methods: in this study a hybrid m...

The lpsA gene, a late acting gene in the biosynthetic pathway of ergovaline, a suspected causative agent for fescue toxicosis in cattle, has been cloned from Neotyphodium lolii, an endophytic fungus of Lolium perenne. In this study, a similar gene was detected in several strains of endophytic Neotyphodium spp. isolated from grass hosts endogenous to Iran using direct and nested-PCR assays. Exce...