conclusions post-operative pain in rectal acetaminophen group was less than that in intravenous acetaminophen group, and rectal acetaminophen group demanded their first additional analgesic medication later. results data analysis indicated a significant relationship between reduction of postoperative pain and the use of intravenous or rectal acetaminophen (p = 0.0001); in group receiving iv ace...

A high sensitive electrochemical nanostructure sensor based on graphene oxide/Fe3O4@SiO2 nanocomposite modified graphite screen printed electrode (GO/Fe3O4@SiO2/SPE) has been developed for trace analysis of acetaminophen. The electrochemical study of the modified electrode, as well as its efficiency for simultaneous voltammetric oxidation of acetaminophen and tryptophan is described. Compared w...

Acetaminophen is a popular over-the-counter analgesic used for headaches and minor musculoskeletal pains. Most persons taking therapeutic doses of acetaminophen experience no side effects. \¥hen taken in greater than the recommended dosage, however, acetaminophen can cause serious complications, including liver and renal failure as well as death. l This outcome is especially evident in those wh...

background: opioid analgesics are the mainstay of the treatment of postoperative pain. appropriate monitoring of patients receiving opioid analgesics is essential to detect those with side effects such as respiratory depression. the discovery of acetaminophen as a cox-3 variant may represent a primary central mechanism by which acetaminophen decrease pain. the aim of this study was to assess th...

Monitoring the acetaminophen in biological samples and also in pharmaceutical formulations is important due to the concerns of public health care and drug safety. In this work a carbon paste electrode modified with BaTiO3 nanoparticle (BTO NPs) and room-temperature ionic liquid (IL) (n-hexyl-3-methylimidazolium hexafluoro phosphate) was fabricated. The direct electro-oxidation behavior of aceta...

Acetaminophen is a widespread and commonly used painkiller all over the world. However, it can cause liver damage when taken in large doses or at repeated chronic doses. Current models of acetaminophen metabolism are complex, and limited to numerical investigation though provide results that represent clinical investigation well. We derive a mathematical model based on mass action laws aimed at...

conclusions administration of intravenous acetaminophen before ending appendectomy might be more effective than meperidine in postoperative pain management while having fewer complications. patients and methods in this randomized clinical trial study, forty patients with asa- class i or ii who were candidates for emergency appendectomy were randomly divided into two groups. induction and mainte...

Objective: The main purpose in the treatment of renal colic patients in emergency department is pain management. This study aimed to compare the analgesic effects of intravenous (IV) acetaminophen and morphine sulfate in this regard. Methods: This double blind clinical trial was conducted on >18 years old renal colic patients in need of pain management in emer...

Sewage sludge treatment has become a primary subject in wastewater treatment and energy production. This paper aims to study the feasibility of power generation by incineration from sewage sludge enriched with impurities like heavy metals. For this purpose, we chose Arak wastewater treatment plant (AWWTP) and used calorific bomb test for examination. The experimental results showed that the hea...