Primary systemic vasculitides (PSV) in children belong to the most challenging conditions in paediatric rheumatology practice. The spectrum of vasculitis affecting children as well as their clinical presentations differ from that of adults. Apart from relatively common Henoch-Shönlein purpura and Kawasaki disease, chronic PSV are extremely rare in childhood. They include mainly childhood polyar...

CONTEXT Vasculitis is a known cause of pancreatitis and other gastrointestinal symptoms; however, most of these patients have medium vessel vasculitis like polyarteritis nodosa and often there are other associated conditions like hepatitis B or clinical manifestations that suggest the diagnosis. Wegener's granulomatosis is predominantly a reno-pulmonary disorder, rarely having gastrointestinal ...

Intestinal involvement of cryoglobulinemia is an uncommon manifestation and marker of severe vasculitis. We describe the case of a woman admitted to our service for management of acute renal failure and progressive gastrointestinal symptoms after initiating hepatitis C virus treatment with ribavirin and sofosbuvir 4 weeks prior. With an undetectable hepatitis C viral load and persistent symptom...

We report the case of an octagenerian who presented with leukocytoclastic vasculitis as the first symptom of Crohn’s disease. The patient was admitted with skin rash on the lower extremities and ankles and episodes of bloody diarrhea. Skin and colon biopsies revealed acute leukocytoclastic vasculitis and moderate Crohn’s disease, respectively. The patient was treated with intravenous corticoste...

Giant cell arteritis is the most common vasculitis in Caucasians. Acute visual loss in one or both eyes is by far the most feared and irreversible complication of giant cell arteritis. This article reviews recent guidelines on early recognition of systemic, cranial, and ophthalmic manifestations, and current management and diagnostic strategies and advances in imaging. We share our experience o...

PURPOSE OF REVIEW In the past decade, primary and secondary central nervous system (CNS) vasculitides have been more commonly diagnosed and recognized than previously. With the increasing awareness of these disorders, it is crucial for the treating physician to differentiate between causes of CNS vasculitis and to recognize their marked clinical and pathophysiological heterogeneity. This review...

Polyarteritis nodosa (PAN) is a rare form of vasculitis. Acute limb ischemia presentation and complication PAN. Plain old balloon angioplasty (POBA) one the treatment strategies when addressing PAN related critical threatening (CLTI). However, recurrence stenosis occlusion frequent poor choice as evidenced in our described clinical case. Consequently, consideration sirolimus’s anti-inflammatory...