Traumatic brain injury (TBI) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of TBI. In the present study, we surveyed the beneficial effec...

background: tumors of the central nervous system (cns) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of cns. objectives: determining the relative frequency of different types of cns tumors in different ages, sex and cns anatomical locations. materials and methods: this retrospective study was performed using pathological repor...

Alcohol directly affects astroglial cell function, including inflammation-related activity.  And it also affects microglial cell development and function in specific ways that interfere with microglial interactions with the immune system and with neurons. Neuroinflammatory processes might be involved in alcohol-induced brain damage. Alcohol use, misuse and getting used to it causes differe...

Introduction: Ferulic acid, a phenolic phytochemical with neuroprotective, anti-inflammatory, and antioxidant properties, has shown promising antidepressant-like effects in behavioral studies; however, its mechanism(s) of action have not been fully understood. Based on the contribution of nerve growth factor (NGF) and endocannabinoid signaling (eCBs) to the emotional or antidepressant activ...

Detection of brain tissues using magnetic resonance imaging (MRI) is an active and challenging research area in computational neuroscience. Brain MRI artifacts lead to an uncertainty in pixel values. Therefore, brain MRI segmentation is a complicated concern which is tackled by a novel data fusion approach. The proposed algorithm has two main steps. In the first step the brain MRI is divided to...

in today's economy of knowledge and globalization, innovation as the ability to apply new knowledge to improve the production process and create new goods and services has been recognized as an undeniable efficiency. a dynamic economy is in need of efficient human capital which includes elites, professionals and entrepreneurs to come up with innovative and competitive ideas. brain drain in some...

objective(s) psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. since studies concerning nerve growth factor (ngf) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on ngf protein levels in various brain regions of rat. materials and methods male wistar rats receiv...