BACKGROUND Vanda tessellata (Orchidaceae) has been used in different sorts of ailments such as inflammations, rheumatism, dysentery, bronchitis, dyspepsia and fever in folk medicine. In this study we evaluated the antinociceptive and cytotoxic effect of methanol and aqueous extracts of V. tessellata leaf. METHODS Oral administration of V. tessellata aqueous (VTA) and methanol (VTM) leaf extra...

In the present study, the crude methanolic extract of whole plant part of Blumea membranacea (Asteraceae) and its fractions obtained by Kupchan method were screened for their possible analgesic, cytotoxic and antioxidant activities. The analgesic activity of the samples was evaluated using acetic acid induced writhing method in Swiss-albino mice. In this method, acetic acid is administered intr...

Background and objectives: Ferula gummosa Boiss. (Umbelliferae) is a popular medicinal plant, which is known mostly for therapeutic uses of its oleo-gum-resin (Barijeh in Persian). In the present study, the essential oil of F. gummosa roots was investigated for its phytochemical constituents, antioxidant activity and toxicity potential. Method...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

The methanol extract of leaves of Urena lobata (L) (Malvaceae) has been selected to determine the antioxidant and cytotoxic potentials. The crude extract were tested for in vitro free radical scavenging assays such as 1, 1 diphenyl-2-picryl-hydrazyl (DPPH). Total phenolic and flavonoids content of U. lobata were analyzed. The sample effectively scavenged free radical at all different concentrat...

OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...

The present study was intended to determine the antioxidant, larvicidal, and cytotoxic potential of various extracts of Asplenium aethiopicum (Burm. f.) Becherer. Antioxidant potential of the extracts was determined by the DPPH radical scavenging, phosphomolybdenum, and scavenging of H2O2. Larvicidal activity of Asplenium aethiopicum was performed against the fourth instar larvae Culex quinquef...

Cacao is a plant that belongs to the Malvaceae family. The n-hexane extract of cocoa pod husks (Theobroma cacao L) and its fraction was determined for cytotoxic activity by Brine Shrimp Lethality Test (BSLT) method which showed very strong activity. Isolation chemical components from Theobroma L. 7.4 (TCH 7.4) TCH 9.1 subfraction obtained with LC50 value 20.39 ppm 5.52 ppm, respectively. compou...

Numerous studies have been focused on natural anticarcinogenic agents. Many antioxidants have been identified as anticarcinogens. Antimutagens have also been proposed as cancer chemopreventive agents. The use of natural products as anticancer has a long history that began with traditional medicine. The aim of this study was to evaluate cytotoxicity and antioxidant activity of twenty-three plant...

Brine shrimp are aquatic crustaceans belonging to a genus of Artemia. This organism is widely used for testing the toxicity of chemicals. In this study, brine shrimp were evaluated as an infection model organism to study bacterial virulence. Artemia nauplii were infected with various pathogenic bacteria, such as Vibrio vulnificus, Pseudomonas aeruginosa, Burkholderia vietnamiensis, Staphylococc...